Xiaosu Chen

State Key Laboratory Of Medicinal Chemical Biology
Changhongjie, China

Last Updated: 09/26/2026

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Found 22 publications

Tumor-Specific Delivery of CD28 siRNA via Lyso-PC C-16 Modified Lipid Nanoparticles Overcomes Anti-PD-1 Resistance by Remodeling Tumor Microenvironment.

Tumor-Specific Delivery of CD28 siRNA via Lyso-PC C-16 Modified Lipid Nanoparticles Overcomes Anti-PD-1 Resistance by Remodeling Tumor Microenvironment.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: March 18, 2026

Systematic profiling of SARS-CoV-2 structural protein-specific T cell epitopes in Omicron infections following inactivated vaccination.

Systematic profiling of SARS-CoV-2 structural protein-specific T cell epitopes in Omicron infections following inactivated vaccination.

Journal: iScience
Published: June 16, 2025

Prolonged Omicron-specific B cell maturation alleviates immune imprinting induced by SARS-CoV-2 inactivated vaccine.

Prolonged Omicron-specific B cell maturation alleviates immune imprinting induced by SARS-CoV-2 inactivated vaccine.

Journal: Emerging microbes & infections
Published: October 03, 2024

Single-cell spatiotemporal analysis reveals alveolar dendritic cell-T cell immunity hubs defending against pulmonary infection.

Single-cell spatiotemporal analysis reveals alveolar dendritic cell-T cell immunity hubs defending against pulmonary infection.

Journal: Cell discovery
Published: June 25, 2024

Single-cell spatiotemporal analysis of the lungs reveals Slamf9+ macrophages involved in viral clearance and inflammation resolution.

Single-cell spatiotemporal analysis of the lungs reveals Slamf9+ macrophages involved in viral clearance and inflammation resolution.

Journal: Cell discovery
Published: June 25, 2024

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1.

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1.

Journal: Nature
Published: June 18, 2024

Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.

Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.

Journal: PLoS pathogens
Published: October 24, 2023

Antigenicity and infectivity characterisation of SARS-CoV-2 BA.2.86.

Antigenicity and infectivity characterisation of SARS-CoV-2 BA.2.86.

Journal: The Lancet. Infectious diseases
Published: September 04, 2023

PAX6/CXCL14 regulatory axis promotes the repair of corneal injury by enhancing corneal epithelial cell proliferation.

PAX6/CXCL14 regulatory axis promotes the repair of corneal injury by enhancing corneal epithelial cell proliferation.

Journal: Journal of translational medicine
Published: July 11, 2023

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting.

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting.

Journal: Nature
Published: May 02, 2023

ACE2 binding and antibody evasion in enhanced transmissibility of XBB.1.5.

ACE2 binding and antibody evasion in enhanced transmissibility of XBB.1.5.

Journal: The Lancet. Infectious diseases
Published: January 02, 2023

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution.

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution.

Journal: Nature
Published: September 23, 2022
Showing 1-12 of 22

Last Updated: 09/26/2026