Xiaoxi Fan

The Key Laboratory Of Cardiovascular Disease Of Wenzhou
Wenzhou, 325000, China

Last Updated: 09/26/2026

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Found 15 publications

Cardiomyocyte-derived USP20 mitigates myocardial ischemia/reperfusion injury through deubiquitinating GRP78.

Cardiomyocyte-derived USP20 mitigates myocardial ischemia/reperfusion injury through deubiquitinating GRP78.

Journal: Theranostics

Published: January 24, 2026

Novel GSDMD inhibitor GI-Y1 attenuates sepsis-induced myocardial dysfunction by targeting Gasdermin D and inhibiting Gasdermin D-mediated pyroptosis.

Novel GSDMD inhibitor GI-Y1 attenuates sepsis-induced myocardial dysfunction by targeting Gasdermin D and inhibiting Gasdermin D-mediated pyroptosis.

Journal: European journal of pharmacology

Published: May 05, 2025

Cardiomyocyte-derived GPX4 stabilizes BNIP3 to facilitate mitophagy and mitigate myocardial ischemia/reperfusion injury.

Cardiomyocyte-derived GPX4 stabilizes BNIP3 to facilitate mitophagy and mitigate myocardial ischemia/reperfusion injury.

Journal: Nature communications

Published: January 02, 2025

The novel GSDMD inhibitor GI-Y2 exerts antipyroptotic effects to reduce atherosclerosis.

The novel GSDMD inhibitor GI-Y2 exerts antipyroptotic effects to reduce atherosclerosis.

Journal: Clinical and translational medicine

Published: November 09, 2024

GSDMD Mediates Ang II-Induced Hypertensive Nephropathy by Regulating the GATA2/AQP4 Signaling Pathway.

GSDMD Mediates Ang II-Induced Hypertensive Nephropathy by Regulating the GATA2/AQP4 Signaling Pathway.

Journal: Journal of inflammation research

Published: August 21, 2024

Gastrointestinal and intraperitoneal bleeding due to multiple pseudoaneurysms postpartial pancreatectomy: A case report and literature review.

Gastrointestinal and intraperitoneal bleeding due to multiple pseudoaneurysms postpartial pancreatectomy: A case report and literature review.

Journal: Radiology case reports

Published: July 21, 2024

GI-Y2, a novel gasdermin D inhibitor, attenuates sepsis-induced myocardial dysfunction by inhibiting gasdermin D-mediated pyroptosis in macrophages.

GI-Y2, a novel gasdermin D inhibitor, attenuates sepsis-induced myocardial dysfunction by inhibiting gasdermin D-mediated pyroptosis in macrophages.

Journal: British journal of pharmacology

Published: June 20, 2024

Macrophage-Derived GSDMD Plays an Essential Role in Atherosclerosis and Cross Talk Between Macrophages via the Mitochondria-STING-IRF3/NF-κB Axis.

Macrophage-Derived GSDMD Plays an Essential Role in Atherosclerosis and Cross Talk Between Macrophages via the Mitochondria-STING-IRF3/NF-κB Axis.

Journal: Arteriosclerosis, thrombosis, and vascular biology

Published: May 02, 2024

ASS1 enhances anoikis resistance via AMPK/CPT1A-mediated fatty acid metabolism in ovarian cancer.

ASS1 enhances anoikis resistance via AMPK/CPT1A-mediated fatty acid metabolism in ovarian cancer.

Journal: Cancer letters

Published: March 22, 2024

Macrophage-derived GSDMD promotes abdominal aortic aneurysm and aortic smooth muscle cells pyroptosis.

Macrophage-derived GSDMD promotes abdominal aortic aneurysm and aortic smooth muscle cells pyroptosis.

Journal: International immunopharmacology

Published: August 14, 2023

Emodin attenuates cardiomyocyte pyroptosis in doxorubicin-induced cardiotoxicity by directly binding to GSDMD.

Emodin attenuates cardiomyocyte pyroptosis in doxorubicin-induced cardiotoxicity by directly binding to GSDMD.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: May 06, 2023

Novel GSDMD inhibitor GI-Y1 protects heart against pyroptosis and ischemia/reperfusion injury by blocking pyroptotic pore formation.

Novel GSDMD inhibitor GI-Y1 protects heart against pyroptosis and ischemia/reperfusion injury by blocking pyroptotic pore formation.

Journal: Basic research in cardiology

Published: April 20, 2023

Showing 1-12 of 15

Last Updated: 09/26/2026