Xiaoyu Shi

State Key Laboratory Of Discovery And Utilization Of Functional Components In Traditional Chinese Medicine, 44 West Culture Road, P.R. China
Jinan, 250012, China

Last Updated: 09/26/2026

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Found 16 publications

Pyridoimidazolyl Sulfonamide Compound 2: A Superior Dual-Acting Drug Candidate with Potent URAT1 Inhibition and Anti-Inflammatory Activity for Gout Management.

Pyridoimidazolyl Sulfonamide Compound 2: A Superior Dual-Acting Drug Candidate with Potent URAT1 Inhibition and Anti-Inflammatory Activity for Gout Management.

Journal: Journal of medicinal chemistry

Published: May 26, 2026

A Novel Pyrrole Acylsulfonamide, Compound 42, as a Dual URAT1/GLUT9 Inhibitor: Potent Urate-Lowering Efficacy, Reduced Off-Target Effects, and Promising Druggability for Hyperuricemia.

A Novel Pyrrole Acylsulfonamide, Compound 42, as a Dual URAT1/GLUT9 Inhibitor: Potent Urate-Lowering Efficacy, Reduced Off-Target Effects, and Promising Druggability for Hyperuricemia.

Journal: Journal of medicinal chemistry

Published: April 17, 2026

.Electrochemical Sensing of 8-Hydroxy-2'-deoxyguanosine with a Portable Cu Metal Hydroxide Organic Framework Saliva Kit: Toward At-Home Oral Cancer Monitoring.

.Electrochemical Sensing of 8-Hydroxy-2'-deoxyguanosine with a Portable Cu Metal Hydroxide Organic Framework Saliva Kit: Toward At-Home Oral Cancer Monitoring.

Journal: ACS sensors

Published: April 15, 2026

Association of systolic blood pressure variability per unit time with new-onset cardiovascular disease - Evidence from CHARLS.

Association of systolic blood pressure variability per unit time with new-onset cardiovascular disease - Evidence from CHARLS.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD

Published: September 26, 2025

Urate transporters: Structural mechanisms and therapeutic opportunities in drug development.

Urate transporters: Structural mechanisms and therapeutic opportunities in drug development.

Journal: Acta pharmaceutica Sinica. B

Published: August 20, 2025

TLR4/NF-κB signaling-mediated neuroinflammation is associated with gut microbiota dysbiosis in a mouse model of Parkinson's disease.

TLR4/NF-κB signaling-mediated neuroinflammation is associated with gut microbiota dysbiosis in a mouse model of Parkinson's disease.

Journal: Frontiers in immunology

Published: July 25, 2025

Clinical insight-driven novel drug development: Multidisciplinary integration and transformative opportunities.

Clinical insight-driven novel drug development: Multidisciplinary integration and transformative opportunities.

Journal: Acta pharmaceutica Sinica. B

Published: May 29, 2025

Molecular basis of the urate transporter URAT1 inhibition by gout drugs.

Molecular basis of the urate transporter URAT1 inhibition by gout drugs.

Journal: bioRxiv : the preprint server for biology

Published: September 24, 2024

Molecular basis of the urate transporter URAT1 inhibition by gout drugs.

Molecular basis of the urate transporter URAT1 inhibition by gout drugs.

Journal: Nature communications

Published: September 10, 2024

Discovery of multi-target anti-gout agents from Eurycoma longifolia Jack through phenotypic screening and structural optimization.

Discovery of multi-target anti-gout agents from Eurycoma longifolia Jack through phenotypic screening and structural optimization.

Journal: Nature communications

Published: July 31, 2024

Iron-doped diesel exhaust early-in-life inhalation-induced cardiopulmonary toxicity in chicken embryo: Roles of ferroptosis and acyl hydrocarbon signaling.

Iron-doped diesel exhaust early-in-life inhalation-induced cardiopulmonary toxicity in chicken embryo: Roles of ferroptosis and acyl hydrocarbon signaling.

Journal: Environmental pollution (Barking, Essex : 1987)

Published: July 28, 2024

Directionally Exfoliated Ni/Co Hydroxide-Organic Framework Nanosheets for Enhanced Wearable Glucose Sensing.

Directionally Exfoliated Ni/Co Hydroxide-Organic Framework Nanosheets for Enhanced Wearable Glucose Sensing.

Journal: Langmuir : the ACS journal of surfaces and colloids

Published: July 19, 2024

Showing 1-12 of 16

Last Updated: 09/26/2026