Xin K. Shen

Wenzhou, China

Last Updated: 09/26/2026

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Found 12 publications

Panobinostat potentiates adagrasib-induced cell death by triggering autophagy in human non-small cell lung cancer.

Panobinostat potentiates adagrasib-induced cell death by triggering autophagy in human non-small cell lung cancer.

Journal: Cell death discovery
Published: March 10, 2025

Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.

Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: January 09, 2024

Impact of High Sodium Diet on Neovascularization and Osseointegration around Titanium Implant: An in Vivo and in Vitro Study.

Impact of High Sodium Diet on Neovascularization and Osseointegration around Titanium Implant: An in Vivo and in Vitro Study.

Journal: Biomedical and environmental sciences : BES
Published: October 08, 2023

Combination of TrxR1 inhibitor and lenvatinib triggers ROS-dependent cell death in human lung cancer cells.

Combination of TrxR1 inhibitor and lenvatinib triggers ROS-dependent cell death in human lung cancer cells.

Journal: International journal of biological sciences
Published: May 14, 2023

Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.

Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.

Journal: Cell death discovery
Published: May 03, 2023

Compensatory combination of mTOR and TrxR inhibitors to cause oxidative stress and regression of tumors.

Compensatory combination of mTOR and TrxR inhibitors to cause oxidative stress and regression of tumors.

Journal: Theranostics
Published: August 17, 2020

Isodeoxyelephantopin Inactivates Thioredoxin Reductase 1 and Activates ROS-Mediated JNK Signaling Pathway to Exacerbate Cisplatin Effectiveness in Human Colon Cancer Cells.

Isodeoxyelephantopin Inactivates Thioredoxin Reductase 1 and Activates ROS-Mediated JNK Signaling Pathway to Exacerbate Cisplatin Effectiveness in Human Colon Cancer Cells.

Journal: Frontiers in cell and developmental biology
Published: July 06, 2020

Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells.

Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells.

Journal: Cellular oncology (Dordrecht, Netherlands)
Published: August 13, 2019

Enhancement of oxaliplatin-induced colon cancer cell apoptosis by alantolactone, a natural product inducer of ROS.

Enhancement of oxaliplatin-induced colon cancer cell apoptosis by alantolactone, a natural product inducer of ROS.

Journal: International journal of biological sciences
Published: March 27, 2019

Curcuminoid WZ26, a TrxR1 inhibitor, effectively inhibits colon cancer cell growth and enhances cisplatin-induced cell death through the induction of ROS.

Curcuminoid WZ26, a TrxR1 inhibitor, effectively inhibits colon cancer cell growth and enhances cisplatin-induced cell death through the induction of ROS.

Journal: Free radical biology & medicine
Published: March 25, 2019

Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells.

Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells.

Journal: Journal of experimental & clinical cancer research : CR
Published: February 10, 2019

Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.

Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.

Journal: Free radical research
Published: January 23, 2019
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Last Updated: 09/26/2026