Xinhua H. Liu

81, Meishan Road
Hefei, 230032, China

Last Updated: 09/26/2026

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Found 113 publications

Role of semaphorin 4f in cardiac fibroblasts to regulate matrix production through actin remodeling and YAP/TAZ activation.

Role of semaphorin 4f in cardiac fibroblasts to regulate matrix production through actin remodeling and YAP/TAZ activation.

Journal: Apoptosis : an international journal on programmed cell death

Published: May 24, 2026

Discovery of novel hydroxycamptothecin derivatives as potent Topo I inhibitors for antitumor guided by molecular dynamics.

Discovery of novel hydroxycamptothecin derivatives as potent Topo I inhibitors for antitumor guided by molecular dynamics.

Journal: European journal of medicinal chemistry

Published: May 13, 2026

Structure-Based Drug Design to Identify Potent, Selective, and Orally Available Cyclin-Dependent Kinase 9 Inhibitors for the Treatment of Castration-Resistant Prostate Cancer.

Structure-Based Drug Design to Identify Potent, Selective, and Orally Available Cyclin-Dependent Kinase 9 Inhibitors for the Treatment of Castration-Resistant Prostate Cancer.

Journal: Journal of medicinal chemistry

Published: May 04, 2026

Discovery of a novel benzoselenophene derivative as a potential therapeutic agent for pulmonary fibrosis.

Discovery of a novel benzoselenophene derivative as a potential therapeutic agent for pulmonary fibrosis.

Journal: European journal of medicinal chemistry

Published: April 30, 2026

Discovery of a potent dual-target CDK8 and cyclin C PROTAC degrader for the treatment of colorectal cancer.

Discovery of a potent dual-target CDK8 and cyclin C PROTAC degrader for the treatment of colorectal cancer.

Journal: RSC medicinal chemistry

Published: April 10, 2026

Discovery of a novel CDK8 inhibitor as dual suppressor of NF-κB-driven inflammation and promoter of Treg differentiation for psoriasis treatment.

Discovery of a novel CDK8 inhibitor as dual suppressor of NF-κB-driven inflammation and promoter of Treg differentiation for psoriasis treatment.

Journal: Bioorganic chemistry

Published: April 06, 2026

Discovery and Evaluation of a PROTAC Degrader Targeting SAMHD1 for the Treatment of Pulmonary Fibrosis.

Discovery and Evaluation of a PROTAC Degrader Targeting SAMHD1 for the Treatment of Pulmonary Fibrosis.

Journal: Journal of medicinal chemistry

Published: April 03, 2026

Sema4A Protects Against Muscle Atrophy and Promotes Repair by Regulating Intracellular Metabolic Signalling.

Sema4A Protects Against Muscle Atrophy and Promotes Repair by Regulating Intracellular Metabolic Signalling.

Journal: Journal of cachexia, sarcopenia and muscle

Published: January 28, 2026

Astilbin directly targets trimethylguanosine synthase 1 to enhance telomerase activity thus alleviating pulmonary fibrosis.

Astilbin directly targets trimethylguanosine synthase 1 to enhance telomerase activity thus alleviating pulmonary fibrosis.

Journal: European journal of pharmacology

Published: January 15, 2026

NOD1/2 signaling in macrophages drives adaptive immune resistance in cancer.

NOD1/2 signaling in macrophages drives adaptive immune resistance in cancer.

Journal: Signal transduction and targeted therapy

Published: November 30, 2025

SEMA3E promotes beige adipocyte differentiation and thermogenesis via β-catenin signaling in mice.

SEMA3E promotes beige adipocyte differentiation and thermogenesis via β-catenin signaling in mice.

Journal: Apoptosis : an international journal on programmed cell death

Published: October 16, 2025

Design and synthesis of a 1,3,6-trimethyl-1H-benzo[d]imidazole-5-sulfonamide derivative as a type I CDK8 inhibitor against colorectal cancer.

Design and synthesis of a 1,3,6-trimethyl-1H-benzo[d]imidazole-5-sulfonamide derivative as a type I CDK8 inhibitor against colorectal cancer.

Journal: Bioorganic chemistry

Published: October 09, 2025

Showing 1-12 of 113

Last Updated: 09/26/2026