Xiong Xie

No. 19A Yuquan Road
Yuquan, 100049, China

Last Updated: 09/26/2026

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Found 15 publications

Exploring chemical space based on Transformation to design broad-spectrum 3CLpro inhibitors against coronavirus.

Exploring chemical space based on Transformation to design broad-spectrum 3CLpro inhibitors against coronavirus.

Journal: European journal of medicinal chemistry

Published: April 22, 2026

Discovery, Optimization, and Evaluation of Novel ANGPTL3 Modulators for the Treatment of Hyperlipidemia.

Discovery, Optimization, and Evaluation of Novel ANGPTL3 Modulators for the Treatment of Hyperlipidemia.

Journal: Journal of medicinal chemistry

Published: September 16, 2025

Development of Orally Bioavailable Octahydroindole-Based Peptidomimetic Derivative as a Broad-Spectrum Inhibitor against HCoV-OC43 and SARS-CoV-2.

Development of Orally Bioavailable Octahydroindole-Based Peptidomimetic Derivative as a Broad-Spectrum Inhibitor against HCoV-OC43 and SARS-CoV-2.

Journal: Journal of medicinal chemistry

Published: May 22, 2025

Discovery of Novel Sulfonylurea NLRP3 Inflammasome Inhibitor for the Treatment of Multiple Inflammatory Diseases.

Discovery of Novel Sulfonylurea NLRP3 Inflammasome Inhibitor for the Treatment of Multiple Inflammatory Diseases.

Journal: Journal of medicinal chemistry

Published: March 20, 2025

Research progress on critical viral protease inhibitors for coronaviruses and enteroviruses.

Research progress on critical viral protease inhibitors for coronaviruses and enteroviruses.

Journal: Bioorganic & medicinal chemistry letters

Published: October 29, 2024

Substrate recognition and cleavage mechanism of the monkeypox virus core protease.

Substrate recognition and cleavage mechanism of the monkeypox virus core protease.

Journal: Nature

Published: October 08, 2024

Palladium(II)-Catalyzed Tandem γ-C(sp2)-H Arylation and Cyclization for the Construction of Natural Product-Like Polycyclic Fused ortho-Quinone Scaffolds.

Palladium(II)-Catalyzed Tandem γ-C(sp2)-H Arylation and Cyclization for the Construction of Natural Product-Like Polycyclic Fused ortho-Quinone Scaffolds.

Journal: Organic letters

Published: April 12, 2024

Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1.

Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1.

Journal: Signal transduction and targeted therapy

Published: July 12, 2023

Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms.

Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms.

Journal: Chemical communications (Cambridge, England)

Published: December 22, 2022

Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability.

Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability.

Journal: Journal of medicinal chemistry

Published: December 06, 2022

In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2.

In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2.

Journal: Antiviral research

Published: July 24, 2022

Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.

Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.

Journal: Journal of medicinal chemistry

Published: April 19, 2022

Showing 1-12 of 15

Last Updated: 09/26/2026