Xishan Wu

No. 190 Kaiyuan Avenue, Guangzhou Science Park
Guangzhou, 510530, China

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 19 publications

Discovery of a Highly Potent and Efficient BRD9 Degrader with Strong In Vivo Antitumor Activity.

Discovery of a Highly Potent and Efficient BRD9 Degrader with Strong In Vivo Antitumor Activity.

Journal: Journal of medicinal chemistry

Published: May 28, 2026

PROTAC technology: clinical applications, future challenges, and innovative strategies.

PROTAC technology: clinical applications, future challenges, and innovative strategies.

Journal: Bioorganic chemistry

Published: January 31, 2026

Key imidazolyl groups that induce phenylalanine flipping enhance the efficacy of oral BRD9 inhibitors for AML treatment.

Key imidazolyl groups that induce phenylalanine flipping enhance the efficacy of oral BRD9 inhibitors for AML treatment.

Journal: Acta pharmaceutica Sinica. B

Published: January 16, 2025

Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer.

Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer.

Journal: Journal of medicinal chemistry

Published: January 02, 2025

Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors.

Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors.

Journal: Journal of medicinal chemistry

Published: November 27, 2024

Discovery of a Promising CBP/p300 Degrader XYD129 for the Treatment of Acute Myeloid Leukemia.

Discovery of a Promising CBP/p300 Degrader XYD129 for the Treatment of Acute Myeloid Leukemia.

Journal: Journal of medicinal chemistry

Published: June 03, 2024

Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity.

Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity.

Journal: Journal of medicinal chemistry

Published: April 22, 2024

Optimization of the synthesis of BET BD2 selective inhibitor XY153.

Optimization of the synthesis of BET BD2 selective inhibitor XY153.

Journal: Chemistry & biodiversity

Published: October 08, 2023

Discovery of a potent and selective CBP bromodomain inhibitor (Y08262) for treating acute myeloid leukemia.

Discovery of a potent and selective CBP bromodomain inhibitor (Y08262) for treating acute myeloid leukemia.

Journal: Bioorganic chemistry

Published: September 24, 2023

Rational design, synthesis and biological evaluation of benzo[d]isoxazole derivatives as potent BET bivalent inhibitors for potential treatment of prostate cancer.

Rational design, synthesis and biological evaluation of benzo[d]isoxazole derivatives as potent BET bivalent inhibitors for potential treatment of prostate cancer.

Journal: Bioorganic chemistry

Published: February 17, 2023

Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain.

Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain.

Journal: Biochemical and biophysical research communications

Published: June 28, 2022

Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist.

Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist.

Journal: Journal of medicinal chemistry

Published: May 04, 2022

Showing 1-12 of 19

Last Updated: 09/26/2026