Xiubin He

State Key Laboratory And Key Laboratory Of Vision Science, Ministry Of Health And Zhejiang Provincial Key Laboratory Of Ophthalmology And Optometry
Wenzhou, China

Last Updated: 09/26/2026

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Found 11 publications

Engineered FnCas12a with enhanced activity through directional evolution in human cells.

Engineered FnCas12a with enhanced activity through directional evolution in human cells.

Journal: The Journal of biological chemistry

Published: October 22, 2020

Boosting activity of high-fidelity CRISPR/Cas9 variants using a tRNAGln-processing system in human cells.

Boosting activity of high-fidelity CRISPR/Cas9 variants using a tRNAGln-processing system in human cells.

Journal: The Journal of biological chemistry

Published: January 30, 2019

Basic and Clinical Application of Adeno-Associated Virus-Mediated Genome Editing.

Basic and Clinical Application of Adeno-Associated Virus-Mediated Genome Editing.

Journal: Human gene therapy

Published: December 28, 2018

Efficient Human Genome Editing Using SaCas9 Ribonucleoprotein Complexes.

Efficient Human Genome Editing Using SaCas9 Ribonucleoprotein Complexes.

Journal: Biotechnology journal

Published: November 19, 2018

Engineering the Direct Repeat Sequence of crRNA for Optimization of FnCpf1-Mediated Genome Editing in Human Cells.

Engineering the Direct Repeat Sequence of crRNA for Optimization of FnCpf1-Mediated Genome Editing in Human Cells.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: March 10, 2018

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

Journal: Biotechnology journal

Published: February 06, 2018

Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells.

Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells.

Journal: Journal of genetics and genomics = Yi chuan xue bao

Published: January 07, 2018

Genome-editing: focus on the off-target effects

Genome-editing: focus on the off-target effects

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology

Published: October 31, 2017

Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation.

Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation.

Journal: Frontiers in molecular neuroscience

Published: October 23, 2017

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

Journal: Biotechnology journal

Published: September 03, 2017

A 'new lease of life': FnCpf1 possesses DNA cleavage activity for genome editing in human cells.

A 'new lease of life': FnCpf1 possesses DNA cleavage activity for genome editing in human cells.

Journal: Nucleic acids research

Published: April 07, 2017

Showing 1-11 of 11

Last Updated: 09/26/2026