Xiuyan Yang
Shanghai, 200025, China
Last Updated: 09/26/2026
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Found 13 publications
Hepatic SIRT6 Deficiency Accelerates Female-Specific Aging Through SULT1E1-Mediated Estrogen Depletion.
Journal: International journal of molecular sciences
Published: June 07, 2026
Enhancing cyclic peptide functionality with hydrophilic diamino acids for improved APC-Asef interaction inhibition.
Journal: Bioorganic & medicinal chemistry
Published: April 08, 2025
Rational design of small-sized peptidomimetic inhibitors disrupting protein-protein interaction.
Journal: RSC medicinal chemistry
Published: March 25, 2024
Discovery of a potent and highly selective inhibitor of SIRT6 against pancreatic cancer metastasis in vivo.
Journal: Acta pharmaceutica Sinica. B
Published: July 17, 2023
Why are heterocycles so special in medicinal chemistry?
Journal: Chemical biology & drug design
Published: October 20, 2022
Rational design of a sensitivity-enhanced tracer for discovering efficient APC-Asef inhibitors.
Journal: Nature communications
Published: November 25, 2021
Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells.
Journal: Acta pharmaceutica Sinica. B
Published: May 17, 2021
Advances and Insights of APC-Asef Inhibitors for Metastatic Colorectal Cancer Therapy.
Journal: Frontiers in molecular biosciences
Published: February 01, 2021
Reply to: Binding site for MDL-801 on SIRT6.
Journal: Nature chemical biology
Published: July 11, 2020
Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors.
Journal: Chemical biology & drug design
Published: September 29, 2018
Identification of a cellularly active SIRT6 allosteric activator.
Journal: Nature chemical biology
Published: September 19, 2017
Last Updated: 09/26/2026