Xiwen Gu

State Key Laboratory Of Holistic Integrative Management Of Gastrointestinal Cancers
Xi'an, China

Last Updated: 09/26/2026

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Found 16 publications

Unraveling bidirectional evolution of unstable mitochondrial DNA mutations in hepatocellular carcinoma at single-cell resolution.

Unraveling bidirectional evolution of unstable mitochondrial DNA mutations in hepatocellular carcinoma at single-cell resolution.

Journal: Hepatology (Baltimore, Md.)

Published: June 17, 2024

Genetic complexity underlies clinical heterogeneity: YWTD β-propeller mutations and second-hit modifier mutations in LRP6-related tooth agenesis and ectodermal dysplasia in human.

Genetic complexity underlies clinical heterogeneity: YWTD β-propeller mutations and second-hit modifier mutations in LRP6-related tooth agenesis and ectodermal dysplasia in human.

Journal: Genes & diseases

Published: April 07, 2024

IDH1 mutation inhibits differentiation of astrocytes and glioma cells with low oxoglutarate dehydrogenase expression by disturbing α-ketoglutarate-related metabolism and epigenetic modification.

IDH1 mutation inhibits differentiation of astrocytes and glioma cells with low oxoglutarate dehydrogenase expression by disturbing α-ketoglutarate-related metabolism and epigenetic modification.

Journal: Life metabolism

Published: September 05, 2023

Mutational profiling of mitochondrial DNA reveals an epithelial ovarian cancer-specific evolutionary pattern contributing to high oxidative metabolism.

Mutational profiling of mitochondrial DNA reveals an epithelial ovarian cancer-specific evolutionary pattern contributing to high oxidative metabolism.

Journal: Clinical and translational medicine

Published: August 14, 2023

Mutational signature of mtDNA confers mechanistic insight into oxidative metabolism remodeling in colorectal cancer.

Mutational signature of mtDNA confers mechanistic insight into oxidative metabolism remodeling in colorectal cancer.

Journal: Theranostics

Published: September 07, 2022

Metastatic pattern of ovarian cancer delineated by tracing the evolution of mitochondrial DNA mutations.

Metastatic pattern of ovarian cancer delineated by tracing the evolution of mitochondrial DNA mutations.

Journal: Experimental & molecular medicine

Published: September 06, 2022

mitoSomatic: a tool for accurate identification of mitochondrial DNA somatic mutations without paired controls.

mitoSomatic: a tool for accurate identification of mitochondrial DNA somatic mutations without paired controls.

Journal: Molecular oncology

Published: August 11, 2022

Mutational profiling of mtDNA control region reveals tumor-specific evolutionary selection involved in mitochondrial dysfunction.

Mutational profiling of mtDNA control region reveals tumor-specific evolutionary selection involved in mitochondrial dysfunction.

Journal: EBioMedicine

Published: December 07, 2021

mitoDataclean: A machine learning approach for the accurate identification of cross-contamination-derived tumor mitochondrial DNA mutations.

mitoDataclean: A machine learning approach for the accurate identification of cross-contamination-derived tumor mitochondrial DNA mutations.

Journal: International journal of cancer

Published: August 25, 2021

Next-Generation Sequencing-Based Analysis of Urine Cell-Free mtDNA Reveals Aberrant Fragmentation and Mutation Profile in Cancer Patients.

Next-Generation Sequencing-Based Analysis of Urine Cell-Free mtDNA Reveals Aberrant Fragmentation and Mutation Profile in Cancer Patients.

Journal: Clinical chemistry

Published: August 23, 2021

Multiple-level copy number variations in cell-free DNA for prognostic prediction of HCC with radical treatments.

Multiple-level copy number variations in cell-free DNA for prognostic prediction of HCC with radical treatments.

Journal: Cancer science

Published: June 06, 2021

Mitochondrial DNA haplogroup M7 confers a reduced risk of colorectal cancer in a Han population from northern China.

Mitochondrial DNA haplogroup M7 confers a reduced risk of colorectal cancer in a Han population from northern China.

Journal: Journal of cellular and molecular medicine

Published: January 23, 2021

Showing 1-12 of 16

Last Updated: 09/26/2026