Xu-bin Bao

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 17 publications

UBA3 reduction sensitizes cancer cells to NAE inhibitors.

UBA3 reduction sensitizes cancer cells to NAE inhibitors.

Journal: Life science alliance
Published: December 04, 2025

PARP inhibitor YCH1899 activates type I interferon signaling and synergizes with STING agonists in BRCA-proficient tumors.

PARP inhibitor YCH1899 activates type I interferon signaling and synergizes with STING agonists in BRCA-proficient tumors.

Journal: Molecular biomedicine
Published: August 28, 2025

VOPP1, a determinant of the sensitivity of non-small cell lung cancer cells to NAE inhibitors.

VOPP1, a determinant of the sensitivity of non-small cell lung cancer cells to NAE inhibitors.

Journal: European journal of pharmacology
Published: April 30, 2025

Combination of Cbl-b inhibitor NX-1607 and CDK4/6 inhibitor abemaciclib enhances anti-tumor immunity through PLCγ1/ERK-mediated T cell activation.

Combination of Cbl-b inhibitor NX-1607 and CDK4/6 inhibitor abemaciclib enhances anti-tumor immunity through PLCγ1/ERK-mediated T cell activation.

Journal: Cellular signalling
Published: March 10, 2025

UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma.

UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma.

Journal: Biochemical pharmacology
Published: November 19, 2024

The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells via reducing SP1 and BCL-2 expression.

The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells via reducing SP1 and BCL-2 expression.

Journal: Life sciences
Published: October 05, 2024

USP7 V517F mutation as a mechanism of inhibitor resistance.

USP7 V517F mutation as a mechanism of inhibitor resistance.

Journal: Nature communications
Published: August 12, 2024

The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity.

The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity.

Journal: Biochemical and biophysical research communications
Published: March 12, 2024

Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy.

Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy.

Journal: Biochemical pharmacology
Published: December 28, 2023

Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy.

Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy.

Journal: Biochemical pharmacology
Published: December 11, 2023

Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells.

Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells.

Journal: Life sciences
Published: July 07, 2023

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance.

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance.

Journal: EMBO molecular medicine
Published: April 29, 2022
Showing 1-12 of 17

Last Updated: 09/26/2026