Xu Shen

CAS Key Laboratory Of Receptor Research, 555 Zuchongzhi Road
Shanghai, 201203, China

Last Updated: 09/26/2026

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Found 20 publications

TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM.

TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM.

Journal: EBioMedicine

Published: February 13, 2019

TSPA as a novel ATF6α translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice.

TSPA as a novel ATF6α translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice.

Journal: Biochemical and biophysical research communications

Published: April 01, 2018

HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1α promoter.

HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1α promoter.

Journal: Metabolism: clinical and experimental

Published: November 06, 2017

Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening.

Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening.

Journal: European journal of medicinal chemistry

Published: July 06, 2016

Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice.

Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice.

Journal: European journal of pharmacology

Published: December 22, 2014

Association between cigarette smoking and Parkinson's disease: A meta-analysis.

Association between cigarette smoking and Parkinson's disease: A meta-analysis.

Journal: Archives of gerontology and geriatrics

Published: December 20, 2014

Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor.

Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor.

Journal: The Journal of biological chemistry

Published: December 17, 2014

In Silico Estimation of Chemical Carcinogenicity with Binary and Ternary Classification Methods.

In Silico Estimation of Chemical Carcinogenicity with Binary and Ternary Classification Methods.

Journal: Molecular informatics

Published: September 12, 2014

FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach.

FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach.

Journal: Scientific reports

Published: September 04, 2014

Exploring NAG-thiazoline and its derivatives as inhibitors of chitinolytic β-acetylglucosaminidases.

Exploring NAG-thiazoline and its derivatives as inhibitors of chitinolytic β-acetylglucosaminidases.

Journal: FEBS letters

Published: September 01, 2014

Novel approaches to drug discovery for the treatment of type 2 diabetes.

Novel approaches to drug discovery for the treatment of type 2 diabetes.

Journal: Expert opinion on drug discovery

Published: July 24, 2014

Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways.

Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways.

Journal: Acta pharmacologica Sinica

Published: February 11, 2014

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Last Updated: 09/26/2026