Xuben T. Hou

44 West Wenhua Road
Jinan, 250012, China

Last Updated: 09/26/2026

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Found 90 publications

Targeting SIRT6: the design and therapeutic implications of activators and inhibitors.

Targeting SIRT6: the design and therapeutic implications of activators and inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: June 21, 2026

Discovery of Benzofuran-2-Carboxylic Acid Derivatives as Potent PTPRO Inhibitors with Oral Efficacy for Treatment of Inflammatory Bowel Disease.

Discovery of Benzofuran-2-Carboxylic Acid Derivatives as Potent PTPRO Inhibitors with Oral Efficacy for Treatment of Inflammatory Bowel Disease.

Journal: Journal of medicinal chemistry

Published: April 28, 2026

WeMol: A Cloud-Based and Zero-Code Platform for AI-Driven Molecular Design and Simulation.

WeMol: A Cloud-Based and Zero-Code Platform for AI-Driven Molecular Design and Simulation.

Journal: Journal of chemical information and modeling

Published: February 11, 2026

Targeting N1-methyladenosine modification in osteoblasts through tRNA methyltransferase 10C reverses mitochondrial dysfunction and ameliorates osteoporosis.

Targeting N1-methyladenosine modification in osteoblasts through tRNA methyltransferase 10C reverses mitochondrial dysfunction and ameliorates osteoporosis.

Journal: Signal transduction and targeted therapy

Published: November 04, 2025

Discovery of 6-substituted indole and tetrahydroquinoline derivatives as selective HDAC8 inhibitors.

Discovery of 6-substituted indole and tetrahydroquinoline derivatives as selective HDAC8 inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: October 01, 2025

Label-free fluorescence lateral flow biosensing platform based on host-guest recognition for on-site detection of amantadine in egg samples.

Label-free fluorescence lateral flow biosensing platform based on host-guest recognition for on-site detection of amantadine in egg samples.

Journal: Food chemistry

Published: September 23, 2025

Cellular Senescence and Aging: Mechanisms, Disease Convergence, and Therapeutic Frontiers.

Cellular Senescence and Aging: Mechanisms, Disease Convergence, and Therapeutic Frontiers.

Journal: MedComm

Published: August 20, 2025

A novel ionizable lipid with comprehensive improvements in transfection potency, immune profile and safety of lipid nanoparticle.

A novel ionizable lipid with comprehensive improvements in transfection potency, immune profile and safety of lipid nanoparticle.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: August 07, 2025

Optimizing pyrazine-2-carboxamide derivatives as dual FLT3/HDAC inhibitors with enhanced pharmacokinetics and immunotherapeutic potential.

Optimizing pyrazine-2-carboxamide derivatives as dual FLT3/HDAC inhibitors with enhanced pharmacokinetics and immunotherapeutic potential.

Journal: Acta pharmaceutica Sinica. B

Published: June 16, 2025

Trimbody with rigid AI-designed scaffolds enables atomic-resolution cryo-EM structure determination of small proteins.

Trimbody with rigid AI-designed scaffolds enables atomic-resolution cryo-EM structure determination of small proteins.

Journal: Nature communications

Published: June 13, 2025

Histone deacetylase enzyme activity is not the universal anticancer target of HDAC inhibitors.

Histone deacetylase enzyme activity is not the universal anticancer target of HDAC inhibitors.

Journal: Signal transduction and targeted therapy

Published: May 29, 2025

Discovery of benzimidazole-based Mcl-1 inhibitors via AlphaShape-enabled virtual screening.

Discovery of benzimidazole-based Mcl-1 inhibitors via AlphaShape-enabled virtual screening.

Journal: European journal of medicinal chemistry

Published: May 23, 2025

Showing 1-12 of 90

Last Updated: 09/26/2026