Xuedong Li

Shijiazhuang, 050017, China

Last Updated: 09/26/2026

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Found 13 publications

Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket.

Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket.

Journal: Journal of medicinal chemistry

Published: February 19, 2026

Design, synthesis, and biological evaluation of selective HDAC6 inhibitors featuring an N-benzyl-2-(aryl/heteroaryl)acetamide cap.

Design, synthesis, and biological evaluation of selective HDAC6 inhibitors featuring an N-benzyl-2-(aryl/heteroaryl)acetamide cap.

Journal: Bioorganic chemistry

Published: January 09, 2026

In silico discovery and biological evaluation of a novel selective HDAC8 inhibitor featuring 1H-pyrazolo[3,4-b]pyridine scaffold.

In silico discovery and biological evaluation of a novel selective HDAC8 inhibitor featuring 1H-pyrazolo[3,4-b]pyridine scaffold.

Journal: Bioorganic chemistry

Published: December 30, 2025

RadioPharm: the database of radiopharmaceuticals.

RadioPharm: the database of radiopharmaceuticals.

Journal: Nucleic acids research

Published: August 09, 2025

The Kv4.3 channel on c-low threshold mechanoreceptors in DRG is a key mediator transforming tactile stimuli into nociceptive signals in chemotherapy-induced neuropathy.

The Kv4.3 channel on c-low threshold mechanoreceptors in DRG is a key mediator transforming tactile stimuli into nociceptive signals in chemotherapy-induced neuropathy.

Journal: Acta pharmaceutica Sinica. B

Published: June 05, 2025

Unveiling the bioactive landscape of drug inactive ingredients (DIGs) using deep transfer learning.

Unveiling the bioactive landscape of drug inactive ingredients (DIGs) using deep transfer learning.

Journal: Acta pharmaceutica Sinica. B

Published: May 29, 2025

Discovery of selective HDAC6 inhibitors driven by artificial intelligence and molecular dynamics simulation approaches.

Discovery of selective HDAC6 inhibitors driven by artificial intelligence and molecular dynamics simulation approaches.

Journal: Journal of pharmaceutical analysis

Published: November 04, 2024

Discovery of E0199: A novel compound targeting both peripheral NaV and KV7 channels to alleviate neuropathic pain.

Discovery of E0199: A novel compound targeting both peripheral NaV and KV7 channels to alleviate neuropathic pain.

Journal: Journal of pharmaceutical analysis

Published: May 02, 2024

Design, Synthesis, and biological evaluation of HDAC6 inhibitors based on Cap modification strategy.

Design, Synthesis, and biological evaluation of HDAC6 inhibitors based on Cap modification strategy.

Journal: Bioorganic chemistry

Published: February 12, 2022

Do biological activities of selective histone deacetylase 6 (HDAC6) inhibitors rely on the modification of cap group?

Do biological activities of selective histone deacetylase 6 (HDAC6) inhibitors rely on the modification of cap group?

Journal: Journal of molecular recognition : JMR

Published: January 04, 2022

Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain.

Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain.

Journal: Frontiers in pharmacology

Published: July 20, 2021

Unveiling the strong dependence of the α-relaxation dispersion on mixing thermodynamics in binary glass-forming liquids.

Unveiling the strong dependence of the α-relaxation dispersion on mixing thermodynamics in binary glass-forming liquids.

Journal: Physical chemistry chemical physics : PCCP

Published: March 03, 2021

Showing 1-12 of 13

Last Updated: 09/26/2026