Xueyang Jiang

Hefei, 230012, China

Last Updated: 09/26/2026

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Found 31 publications

Discovery of SH-17 as a pioneering STAT3/HDAC bifunctional inhibitor that simultaneously impairs Tyr705 and Ser727 phosphorylation.

Discovery of SH-17 as a pioneering STAT3/HDAC bifunctional inhibitor that simultaneously impairs Tyr705 and Ser727 phosphorylation.

Journal: Bioorganic chemistry

Published: March 05, 2026

Borneol-loaded liposomes modified with 5-hydroxy-1H-pyrazole-3-carboxylic acid enhance neuroprotection and brain specific for ischemic stroke therapy.

Borneol-loaded liposomes modified with 5-hydroxy-1H-pyrazole-3-carboxylic acid enhance neuroprotection and brain specific for ischemic stroke therapy.

Journal: Bioorganic & medicinal chemistry

Published: February 28, 2026

Pyrazole carboxylic acid borneol esters: Novel neuroprotective agents with rapid, efficient brain penetration for the treatment of ischemic stroke.

Pyrazole carboxylic acid borneol esters: Novel neuroprotective agents with rapid, efficient brain penetration for the treatment of ischemic stroke.

Journal: European journal of medicinal chemistry

Published: November 26, 2025

Ligustrazine as a multitarget scaffold in drug design and discovery.

Ligustrazine as a multitarget scaffold in drug design and discovery.

Journal: Bioorganic & medicinal chemistry

Published: November 06, 2024

Design, synthesis and biological evaluation of novel pyrazolinone derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Design, synthesis and biological evaluation of novel pyrazolinone derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Journal: Bioorganic chemistry

Published: August 23, 2024

Identification of 3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-5-ol as promising neuroprotective agent.

Identification of 3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-5-ol as promising neuroprotective agent.

Journal: Bioorganic & medicinal chemistry letters

Published: July 27, 2024

Identification and optimization of nitrophenolic analogues as dopamine metabolic enzyme inhibitors for the treatment of Parkinson's disease.

Identification and optimization of nitrophenolic analogues as dopamine metabolic enzyme inhibitors for the treatment of Parkinson's disease.

Journal: Bioorganic chemistry

Published: April 09, 2024

Bioassay-Guided Fractionation and Biological Activity of Cardenolides from Streptocaulon juventas.

Bioassay-Guided Fractionation and Biological Activity of Cardenolides from Streptocaulon juventas.

Journal: Planta medica

Published: September 14, 2023

Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents.

Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents.

Journal: Journal of natural products

Published: August 10, 2023

Design and synthesis of 9-phenanthranilamide derivatives and the study of anti-inflammatory, antioxidant and neuroprotective activities.

Design and synthesis of 9-phenanthranilamide derivatives and the study of anti-inflammatory, antioxidant and neuroprotective activities.

Journal: Bioorganic chemistry

Published: May 23, 2023

Discovery of thiazole salt AChE inhibitors and development of thiamine disulfide prodrugs targeting the central nervous system.

Discovery of thiazole salt AChE inhibitors and development of thiamine disulfide prodrugs targeting the central nervous system.

Journal: Bioorganic chemistry

Published: April 26, 2023

Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment.

Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment.

Journal: European journal of medicinal chemistry

Published: April 20, 2022

Showing 1-12 of 31

Last Updated: 09/26/2026