Xun Lu

Shanghai, 200025, China

Last Updated: 09/26/2026

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Found 15 publications

Design and synthesis of multi-substituted pyrazole derivatives as potential allosteric inhibitors of 3CLpro.

Design and synthesis of multi-substituted pyrazole derivatives as potential allosteric inhibitors of 3CLpro.

Journal: RSC medicinal chemistry
Published: February 27, 2026

Decoding the selective mechanism behind a monobody inhibitor to the phosphatase domain of SHP2: insights from molecular dynamics simulations.

Decoding the selective mechanism behind a monobody inhibitor to the phosphatase domain of SHP2: insights from molecular dynamics simulations.

Journal: Physical chemistry chemical physics : PCCP
Published: April 15, 2025

In silico identification and experimental validation of long-range allosteric inhibition of Staphylococcus aureus Cas9 catalytic activity by an anti-CRISPR protein AcrIIA14.

In silico identification and experimental validation of long-range allosteric inhibition of Staphylococcus aureus Cas9 catalytic activity by an anti-CRISPR protein AcrIIA14.

Journal: International journal of biological macromolecules
Published: February 13, 2025

Qigui-Yishen decoction delays renal fibrosis in mice with chronic kidney disease by regulating TM and PAI-1.

Qigui-Yishen decoction delays renal fibrosis in mice with chronic kidney disease by regulating TM and PAI-1.

Journal: American journal of translational research
Published: March 19, 2024

Deciphering the comprehensive knowledgebase landscape featuring infertility with IDDB Xtra.

Deciphering the comprehensive knowledgebase landscape featuring infertility with IDDB Xtra.

Journal: Computers in biology and medicine
Published: December 20, 2023

Delineating the stepwise millisecond allosteric activation mechanism of the class C GPCR dimer mGlu5.

Delineating the stepwise millisecond allosteric activation mechanism of the class C GPCR dimer mGlu5.

Journal: Nature communications
Published: September 23, 2023

G protein-coupled receptors (GPCRs): advances in structures, mechanisms, and drug discovery.

G protein-coupled receptors (GPCRs): advances in structures, mechanisms, and drug discovery.

Journal: Signal transduction and targeted therapy
Published: August 15, 2023

A Structure-Based Allosteric Modulator Design Paradigm.

A Structure-Based Allosteric Modulator Design Paradigm.

Journal: Health data science
Published: July 02, 2023

Mechanistic Elucidation of Activation/Deactivation Signal Transduction within Neurotensin Receptor 1 Triggered by 'Driver Chemical Groups' of Modulators: A Comparative Molecular Dynamics Simulation.

Mechanistic Elucidation of Activation/Deactivation Signal Transduction within Neurotensin Receptor 1 Triggered by 'Driver Chemical Groups' of Modulators: A Comparative Molecular Dynamics Simulation.

Journal: Pharmaceutics
Published: June 30, 2023

Intensified perfusion culture (IPC) reduced recombinant protein fragmentation.

Intensified perfusion culture (IPC) reduced recombinant protein fragmentation.

Journal: Biotechnology progress
Published: March 05, 2023

DeepAlloDriver: a deep learning-based strategy to predict cancer driver mutations.

DeepAlloDriver: a deep learning-based strategy to predict cancer driver mutations.

Journal: Nucleic acids research
Published: February 19, 2023

AlloReverse: multiscale understanding among hierarchical allosteric regulations.

AlloReverse: multiscale understanding among hierarchical allosteric regulations.

Journal: Nucleic acids research
Published: February 07, 2023
Showing 1-12 of 15

Last Updated: 09/26/2026