Yael Mamane
Saint-laurent, QC H4S2A1, Canada
Last Updated: 09/26/2026
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Found 8 publications
Structure and mechanism of inhibition of lysine demethylase 2A (KDM2A) by compound 183c.
Journal: Communications chemistry
Published: December 17, 2025
Design of a Targeted Covalent Probe to Interrogate the DNA Polymerase Activity of Polθ.
Journal: ACS medicinal chemistry letters
Published: October 25, 2025
The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase Inhibitor.
Journal: Journal of medicinal chemistry
Published: September 08, 2025
Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500).
Journal: Journal of medicinal chemistry
Published: February 01, 2024
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
Journal: Journal of medicinal chemistry
Published: September 20, 2022
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
Journal: Journal of medicinal chemistry
Published: July 26, 2022
RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors.
Journal: Molecular cancer therapeutics
Published: July 19, 2021
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Journal: Nature
Published: April 20, 2021
Showing 1-8 of 8
Last Updated: 09/26/2026