Yajun Yang

Beijing Key Laboratory Of New Drug Mechanisms And Pharmacological Evaluation Study, Chinese Academy Of Medical Science & Peking Union Medical College
Beijing, China

Last Updated: 09/26/2026

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Found 12 publications

Identification of a novel xanthine oxidoreductase inhibitor for hyperuricemia treatment with high efficacy and safety profile.

Identification of a novel xanthine oxidoreductase inhibitor for hyperuricemia treatment with high efficacy and safety profile.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 23, 2024

A System for Discovering Novel Uricosurics Targeting Urate Transporter 1 Based on In Vitro and In Vivo Modeling.

A System for Discovering Novel Uricosurics Targeting Urate Transporter 1 Based on In Vitro and In Vivo Modeling.

Journal: Pharmaceutics

Published: December 22, 2023

Discovery of Novel Metalloenzyme Inhibitors Based on Property Characterization: Strategy and Application for HDAC1 Inhibitors.

Discovery of Novel Metalloenzyme Inhibitors Based on Property Characterization: Strategy and Application for HDAC1 Inhibitors.

Journal: Molecules (Basel, Switzerland)

Published: November 30, 2023

Discovery of Novel Biphenyl Carboxylic Acid Derivatives as Potent URAT1 Inhibitors.

Discovery of Novel Biphenyl Carboxylic Acid Derivatives as Potent URAT1 Inhibitors.

Journal: Molecules (Basel, Switzerland)

Published: October 14, 2023

Myofibrillogenesis Regulator-1 Regulates the Ubiquitin Lysosomal Pathway of Notch3 Intracellular Domain Through E3 Ubiquitin-Protein Ligase Itchy Homolog in the Metastasis of Non-Small Cell Lung Cancer.

Myofibrillogenesis Regulator-1 Regulates the Ubiquitin Lysosomal Pathway of Notch3 Intracellular Domain Through E3 Ubiquitin-Protein Ligase Itchy Homolog in the Metastasis of Non-Small Cell Lung Cancer.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: September 07, 2023

Non-peptidic immunoproteasome β5i-selective inhibitor as potential treatment for idiopathic pulmonary fibrosis: Virtual screening, hit evolution and lead identification.

Non-peptidic immunoproteasome β5i-selective inhibitor as potential treatment for idiopathic pulmonary fibrosis: Virtual screening, hit evolution and lead identification.

Journal: European journal of medicinal chemistry

Published: June 14, 2023

Discovery of novel 1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors with hypouricemic effects.

Discovery of novel 1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors with hypouricemic effects.

Journal: Bioorganic chemistry

Published: June 27, 2022

Identification of N, C-capped di- and tripeptides as selective immunoproteasome inhibitors.

Identification of N, C-capped di- and tripeptides as selective immunoproteasome inhibitors.

Journal: European journal of medicinal chemistry

Published: November 30, 2021

Identification of novel xanthine oxidase inhibitors via virtual screening with enhanced characterization of molybdopterin binding groups.

Identification of novel xanthine oxidase inhibitors via virtual screening with enhanced characterization of molybdopterin binding groups.

Journal: European journal of medicinal chemistry

Published: October 01, 2021

Identification of 3, 4-disubstituted pyridine derivatives as novel CDK8 inhibitors.

Identification of 3, 4-disubstituted pyridine derivatives as novel CDK8 inhibitors.

Journal: European journal of medicinal chemistry

Published: March 03, 2021

Synthesis of High Purified Tulobuterol and Its Study of the Organic Impurities.

Synthesis of High Purified Tulobuterol and Its Study of the Organic Impurities.

Journal: Journal of chromatographic science

Published: October 11, 2017

Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization.

Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization.

Journal: Chemical communications (Cambridge, England)

Published: October 14, 2016

Showing 1-12 of 12

Last Updated: 09/26/2026