Yakun Gu

Beijing, China

Last Updated: 09/26/2026

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Found 14 publications

Intermittent Hypoxia Maintains Neovascular Blood-Brain Barrier Integrity Via the HIF-1α/VEGFB Axis.

Intermittent Hypoxia Maintains Neovascular Blood-Brain Barrier Integrity Via the HIF-1α/VEGFB Axis.

Journal: Translational stroke research
Published: October 14, 2025

Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia.

Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia.

Journal: eLife
Published: June 23, 2025

Novel mechanism of neuronal hypoxia response: HIF-1α/STOML2 mediated PINK1-dependent mitophagy activation against neuronal injury.

Novel mechanism of neuronal hypoxia response: HIF-1α/STOML2 mediated PINK1-dependent mitophagy activation against neuronal injury.

Journal: Cell death discovery
Published: June 18, 2025

Cryopreservation of Medicinal Plant Seeds: Strategies for Genetic Diversity Conservation and Sustainability.

Cryopreservation of Medicinal Plant Seeds: Strategies for Genetic Diversity Conservation and Sustainability.

Journal: Plants (Basel, Switzerland)
Published: August 14, 2024

Intermittent hypoxic perconditioning improves cognitive function in a mouse model of vascular cognitive impairment and dementia with comorbidities by recovering cerebral blood flow.

Intermittent hypoxic perconditioning improves cognitive function in a mouse model of vascular cognitive impairment and dementia with comorbidities by recovering cerebral blood flow.

Journal: Neural regeneration research
Published: June 28, 2024

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment.

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment.

Journal: Neural regeneration research
Published: August 12, 2023

Intermittent hypoxia protects against hypoxic-ischemic brain damage by inducing functional angiogenesis.

Intermittent hypoxia protects against hypoxic-ischemic brain damage by inducing functional angiogenesis.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published: July 03, 2023

Hypoxic stress accelerates the propagation of pathological alpha-synuclein and degeneration of dopaminergic neurons.

Hypoxic stress accelerates the propagation of pathological alpha-synuclein and degeneration of dopaminergic neurons.

Journal: CNS neuroscience & therapeutics
Published: October 02, 2022

Proteomic Analysis Reveals That Mitochondria Dominate the Hippocampal Hypoxic Response in Mice.

Proteomic Analysis Reveals That Mitochondria Dominate the Hippocampal Hypoxic Response in Mice.

Journal: International journal of molecular sciences
Published: September 09, 2022

Chronic hypoxia leads to cognitive impairment by promoting HIF-2α-mediated ceramide catabolism and alpha-synuclein hyperphosphorylation.

Chronic hypoxia leads to cognitive impairment by promoting HIF-2α-mediated ceramide catabolism and alpha-synuclein hyperphosphorylation.

Journal: Cell death discovery
Published: August 22, 2022

Effects of Hypoxia on Cerebral Microvascular Angiogenesis: Benefits or Damages?

Effects of Hypoxia on Cerebral Microvascular Angiogenesis: Benefits or Damages?

Journal: Aging and disease
Published: May 31, 2022

Intermittent hypoxic conditioning restores neurological dysfunction of mice induced by long-term hypoxia.

Intermittent hypoxic conditioning restores neurological dysfunction of mice induced by long-term hypoxia.

Journal: CNS neuroscience & therapeutics
Published: May 12, 2022
Showing 1-12 of 14

Last Updated: 09/26/2026