Yakun Ma

Changhongjie, China

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 11 publications

Sleep Deprivation Exacerbates High-Fat Diet-Induced Obesity and MAFLD Through Melatonin Reduction Mediated NF-κB Activation.

Sleep Deprivation Exacerbates High-Fat Diet-Induced Obesity and MAFLD Through Melatonin Reduction Mediated NF-κB Activation.

Journal: Journal of pineal research

Published: August 29, 2025

Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment.

Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment.

Journal: Journal of medicinal chemistry

Published: July 10, 2025

Novel EGFR inhibitors against resistant L858R/T790M/C797S mutant for intervention of non-small cell lung cancer.

Novel EGFR inhibitors against resistant L858R/T790M/C797S mutant for intervention of non-small cell lung cancer.

Journal: European journal of medicinal chemistry

Published: June 17, 2024

Design, synthesis and biological evaluation of potent epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors against resistance mutation for lung cancer treatment.

Design, synthesis and biological evaluation of potent epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors against resistance mutation for lung cancer treatment.

Journal: Bioorganic chemistry

Published: September 04, 2023

Discovery of 12O-A Novel Oral Multi-Kinase Inhibitor for the Treatment of Solid Tumor.

Discovery of 12O-A Novel Oral Multi-Kinase Inhibitor for the Treatment of Solid Tumor.

Journal: Molecules (Basel, Switzerland)

Published: September 10, 2020

Design, synthesis and biological assessment of novel CDK4 inhibitor with potent anticancer activity.

Design, synthesis and biological assessment of novel CDK4 inhibitor with potent anticancer activity.

Journal: Bioorganic chemistry

Published: August 11, 2020

Novel CDKs inhibitors for the treatment of solid tumour by simultaneously regulating the cell cycle and transcription control.

Novel CDKs inhibitors for the treatment of solid tumour by simultaneously regulating the cell cycle and transcription control.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: January 05, 2020

Novel cyclin-dependent kinase 9 (CDK9) inhibitor with suppression of cancer stemness activity against non-small-cell lung cancer.

Novel cyclin-dependent kinase 9 (CDK9) inhibitor with suppression of cancer stemness activity against non-small-cell lung cancer.

Journal: European journal of medicinal chemistry

Published: April 03, 2019

Preparation and evaluation of highly biocompatible nanogels with pH-sensitive charge-convertible capability based on doxorubicin prodrug.

Preparation and evaluation of highly biocompatible nanogels with pH-sensitive charge-convertible capability based on doxorubicin prodrug.

Journal: Materials science & engineering. C, Materials for biological applications

Published: May 18, 2018

Novel hybrid molecule overcomes the limited response of solid tumours to HDAC inhibitors via suppressing JAK1-STAT3-BCL2 signalling.

Novel hybrid molecule overcomes the limited response of solid tumours to HDAC inhibitors via suppressing JAK1-STAT3-BCL2 signalling.

Journal: Theranostics

Published: April 11, 2018

Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer.

Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer.

Journal: Journal of medicinal chemistry

Published: January 09, 2018

Showing 1-11 of 11

Last Updated: 09/26/2026