Yan-yan Shen

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 16 publications

Petroselinic Acid from Apiaceae Family Plants Ameliorates Autoimmune Disorders Through Suppressing Cytosolic-Nucleic-Acid-Mediated Type I Interferon Signaling.

Petroselinic Acid from Apiaceae Family Plants Ameliorates Autoimmune Disorders Through Suppressing Cytosolic-Nucleic-Acid-Mediated Type I Interferon Signaling.

Journal: Biomolecules
Published: January 14, 2025

Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling.

Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling.

Journal: Nutrients
Published: July 19, 2024

Tauroursodeoxycholic acid targets HSP90 to promote protein homeostasis and extends healthy lifespan.

Tauroursodeoxycholic acid targets HSP90 to promote protein homeostasis and extends healthy lifespan.

Journal: Science China. Life sciences
Published: June 11, 2024

Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities.

Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities.

Journal: European journal of medicinal chemistry
Published: June 05, 2023

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance.

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance.

Journal: EMBO molecular medicine
Published: April 29, 2022

Author Correction: G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin.

Author Correction: G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin.

Journal: Nature communications
Published: July 26, 2020

Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R.

Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R.

Journal: Acta pharmacologica Sinica
Published: April 12, 2018

Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.

Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.

Journal: Cell
Published: November 27, 2017

SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models.

SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models.

Journal: Acta pharmacologica Sinica
Published: May 24, 2017

G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin.

G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin.

Journal: Nature communications
Published: January 03, 2017

Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors.

Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors.

Journal: Acta pharmacologica Sinica
Published: December 27, 2016

Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration.

Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration.

Journal: Acta pharmacologica Sinica
Published: October 02, 2016
Showing 1-12 of 16

Last Updated: 09/26/2026