Yanfen Fang

No. 19A Yuquan Road
Yuquan, 100049, China

Last Updated: 09/26/2026

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Found 31 publications

Rapid Identification of a Potent, Selective, and Orally Active p300/CBP Bromodomain Inhibitor Bearing an Imidazo[1,2-a]pyridine Scaffold via a Highly Efficient Four-Step Synthesis.

Rapid Identification of a Potent, Selective, and Orally Active p300/CBP Bromodomain Inhibitor Bearing an Imidazo[1,2-a]pyridine Scaffold via a Highly Efficient Four-Step Synthesis.

Journal: Journal of medicinal chemistry

Published: July 17, 2026

Discovery of CZL-149: A Novel, Highly Potent, and Orally Bioavailable Dual Inhibitor Targeting BET and p300/CBP Bromodomains with Strong Antitumor Efficacy.

Discovery of CZL-149: A Novel, Highly Potent, and Orally Bioavailable Dual Inhibitor Targeting BET and p300/CBP Bromodomains with Strong Antitumor Efficacy.

Journal: Journal of medicinal chemistry

Published: May 18, 2026

Design and synthesis of dual-target CDK9-EZH2 inhibitors using a pharmacophore fusion strategy.

Design and synthesis of dual-target CDK9-EZH2 inhibitors using a pharmacophore fusion strategy.

Journal: Bioorganic & medicinal chemistry letters

Published: April 14, 2026

Non-canonical function of transferrin receptor-1 promotes breast cancer metastasis by activating HCK‒STAT3‒MMP9 signalling.

Non-canonical function of transferrin receptor-1 promotes breast cancer metastasis by activating HCK‒STAT3‒MMP9 signalling.

Journal: Clinical and translational medicine

Published: March 16, 2026

Marine-Derived Bromotyrosine Alkaloids as Potent hCYP1B1 Inhibitors to Overcome Paclitaxel Resistance.

Marine-Derived Bromotyrosine Alkaloids as Potent hCYP1B1 Inhibitors to Overcome Paclitaxel Resistance.

Journal: Journal of medicinal chemistry

Published: January 30, 2026

Pharmaco-genomic characterization of pancreatic and biliary tract cancer tumoroids for drug response.

Pharmaco-genomic characterization of pancreatic and biliary tract cancer tumoroids for drug response.

Journal: iScience

Published: October 02, 2025

Switching Photocatalytic CO2 Reduction Path via Controlled Surface Hydroxylation in GO/CoTPP Hybrids.

Switching Photocatalytic CO2 Reduction Path via Controlled Surface Hydroxylation in GO/CoTPP Hybrids.

Journal: Inorganic chemistry

Published: September 09, 2025

Discovery of Novel Tridentate Alkenyl Diacid Derivatives as Potent ATP Citrate Lyase Inhibitors for the Treatment of Hepatocellular Carcinoma.

Discovery of Novel Tridentate Alkenyl Diacid Derivatives as Potent ATP Citrate Lyase Inhibitors for the Treatment of Hepatocellular Carcinoma.

Journal: Journal of medicinal chemistry

Published: July 16, 2025

Development of ASGR-Mediated Hepatocyte-Targeting Cytotoxic Drug Conjugates with CTSB-Cleavable Linkers Incorporating Succinimide and Succinic Acid Monoamide.

Development of ASGR-Mediated Hepatocyte-Targeting Cytotoxic Drug Conjugates with CTSB-Cleavable Linkers Incorporating Succinimide and Succinic Acid Monoamide.

Journal: Journal of medicinal chemistry

Published: February 07, 2025

Long-circulating enzyme-activated HSP90-targeted camptothecin derivatives.

Long-circulating enzyme-activated HSP90-targeted camptothecin derivatives.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: November 19, 2024

Facet-induced fractionation of humic acid by hematite and the promoted-photodegradation of 17β-estradiol catalyzed by hematite-humic complex.

Facet-induced fractionation of humic acid by hematite and the promoted-photodegradation of 17β-estradiol catalyzed by hematite-humic complex.

Journal: Journal of hazardous materials

Published: September 09, 2024

BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair.

BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair.

Journal: Translational oncology

Published: July 12, 2024

Showing 1-12 of 31

Last Updated: 09/26/2026