Yang Zhu

Wenzhou, 325027, China

Last Updated: 09/26/2026

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Found 49 publications

Industrial phenolic compounds targeting 11β-hydroxysteroid dehydrogenase 2: A comparative in silico and structure-activity investigation in humans and rats.

Industrial phenolic compounds targeting 11β-hydroxysteroid dehydrogenase 2: A comparative in silico and structure-activity investigation in humans and rats.

Journal: Ecotoxicology and environmental safety

Published: June 15, 2026

Disruption of progesterone synthesis by PBDEs: Potent inhibition of human and rat placental 3β-hydroxysteroid dehydrogenase by the metabolite 4-Bromodiphenyl ether.

Disruption of progesterone synthesis by PBDEs: Potent inhibition of human and rat placental 3β-hydroxysteroid dehydrogenase by the metabolite 4-Bromodiphenyl ether.

Journal: Toxicology and applied pharmacology

Published: May 20, 2026

Insights into the inhibitory mechanisms of alkyl phosphate esters on 3β-hydroxysteroid dehydrogenases: Implications for placental reproductive toxicity.

Insights into the inhibitory mechanisms of alkyl phosphate esters on 3β-hydroxysteroid dehydrogenases: Implications for placental reproductive toxicity.

Journal: Bioorganic chemistry

Published: May 12, 2026

Structure-activity relationship of per- and Polyfluoroalkyl substances as inhibitors of human and rat 17β-Hydroxysteroid dehydrogenase 3.

Structure-activity relationship of per- and Polyfluoroalkyl substances as inhibitors of human and rat 17β-Hydroxysteroid dehydrogenase 3.

Journal: Toxicology and applied pharmacology

Published: May 05, 2026

Structural determinants of paraben-mediated 11β-hydroxysteroid dehydrogenase 1 inhibition: Integrated mechanistic, kinetic and in silico approaches to cortisol metabolism.

Structural determinants of paraben-mediated 11β-hydroxysteroid dehydrogenase 1 inhibition: Integrated mechanistic, kinetic and in silico approaches to cortisol metabolism.

Journal: Toxicology and applied pharmacology

Published: March 22, 2026

Hydrophobicity, 3D complexity, and steric feature affect salicylate inhibition of human and rat gonadal 3β-hydroxysteroid dehydrogenases: Insights from experiments to 3D-QSAR and in silico docking analysis.

Hydrophobicity, 3D complexity, and steric feature affect salicylate inhibition of human and rat gonadal 3β-hydroxysteroid dehydrogenases: Insights from experiments to 3D-QSAR and in silico docking analysis.

Journal: Chemico-biological interactions

Published: December 04, 2025

Species-specific inhibition of human and rat gonadal 3β-hydroxysteroid dehydrogenases by emerging organophosphate esters: A multiscale approach combining in vitro assays and computational modeling.

Species-specific inhibition of human and rat gonadal 3β-hydroxysteroid dehydrogenases by emerging organophosphate esters: A multiscale approach combining in vitro assays and computational modeling.

Journal: Ecotoxicology and environmental safety

Published: November 26, 2025

PINK1-PARKIN-dependent mitophagy links diphenyltin exposure to steroidogenic collapse in Rat Leydig Cells during puberty.

PINK1-PARKIN-dependent mitophagy links diphenyltin exposure to steroidogenic collapse in Rat Leydig Cells during puberty.

Journal: Chemico-biological interactions

Published: October 10, 2025

Inhibition of human and rat placental 3β-hydroxysteroid dehydrogenases by gallates: Combined experimental, 3D-QSAR, and in silico analysis.

Inhibition of human and rat placental 3β-hydroxysteroid dehydrogenases by gallates: Combined experimental, 3D-QSAR, and in silico analysis.

Journal: Bioorganic chemistry

Published: July 10, 2025

Structure activity relationship of Aristolochic acid analogues: Inhibitory effect on human and rat gonadal 3β-Hydroxysteroid dehydrogenases.

Structure activity relationship of Aristolochic acid analogues: Inhibitory effect on human and rat gonadal 3β-Hydroxysteroid dehydrogenases.

Journal: Bioorganic chemistry

Published: April 27, 2025

Inhibition of brain human steroid 5α-reductase 1 by dithiocarbamates: A Comprehensive enzymatic and structural analysis.

Inhibition of brain human steroid 5α-reductase 1 by dithiocarbamates: A Comprehensive enzymatic and structural analysis.

Journal: The Journal of steroid biochemistry and molecular biology

Published: March 24, 2025

Benzophenone UV-filters: Inhibition on human and rat 17β-hydroxysteroid dehydrogenase 1 - insights from 3D-QSAR and docking studies.

Benzophenone UV-filters: Inhibition on human and rat 17β-hydroxysteroid dehydrogenase 1 - insights from 3D-QSAR and docking studies.

Journal: The Journal of steroid biochemistry and molecular biology

Published: January 16, 2025

Showing 1-12 of 49

Last Updated: 09/26/2026