Yani Sim

Wilrijk, VLG 2610, Belgium

Last Updated: 09/26/2026

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Found 12 publications

In vitro kinetic profiling by enzymatic approaches to select FAPIs with a long residence time.

In vitro kinetic profiling by enzymatic approaches to select FAPIs with a long residence time.

Journal: European journal of medicinal chemistry

Published: September 24, 2025

Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase-1- and Gasdermin-Dependent Cell Death.

Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase-1- and Gasdermin-Dependent Cell Death.

Journal: European journal of immunology

Published: September 19, 2024

Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active.

Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active.

Journal: Journal of extracellular vesicles

Published: November 02, 2023

ProCPU Is Expressed by (Primary) Human Monocytes and Macrophages and Expression Differs between States of Differentiation and Activation.

ProCPU Is Expressed by (Primary) Human Monocytes and Macrophages and Expression Differs between States of Differentiation and Activation.

Journal: International journal of molecular sciences

Published: December 13, 2022

Atorvastatin downregulates plasma procarboxypeptidase U concentrations and improves fibrinolytic potential dose-dependently in hyperlipidemic individuals.

Atorvastatin downregulates plasma procarboxypeptidase U concentrations and improves fibrinolytic potential dose-dependently in hyperlipidemic individuals.

Journal: Journal of thrombosis and haemostasis : JTH

Published: June 29, 2022

Activation of the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients with SARS-CoV-2 Infection Could Contribute to COVID-19 Hypofibrinolytic State and Disease Severity Prognosis.

Activation of the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients with SARS-CoV-2 Infection Could Contribute to COVID-19 Hypofibrinolytic State and Disease Severity Prognosis.

Journal: Journal of clinical medicine

Published: January 10, 2022

Pleiotropic Effects of Atorvastatin Result in a Downregulation of the Carboxypeptidase U System (CPU, TAFIa, CPB2) in a Mouse Model of Advanced Atherosclerosis.

Pleiotropic Effects of Atorvastatin Result in a Downregulation of the Carboxypeptidase U System (CPU, TAFIa, CPB2) in a Mouse Model of Advanced Atherosclerosis.

Journal: Pharmaceutics

Published: September 13, 2021

Inhibition of the procarboxypeptidase U (proCPU, TAFI, proCPB2) system due to hemolysis.

Inhibition of the procarboxypeptidase U (proCPU, TAFI, proCPB2) system due to hemolysis.

Journal: Journal of thrombosis and haemostasis : JTH

Published: January 12, 2019

Plasma carboxypeptidase U (CPU, CPB2, TAFIa) generation during in vitro clot lysis and its interplay between coagulation and fibrinolysis.

Plasma carboxypeptidase U (CPU, CPB2, TAFIa) generation during in vitro clot lysis and its interplay between coagulation and fibrinolysis.

Journal: Thrombosis and haemostasis

Published: February 13, 2017

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme.

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme.

Journal: Biochimica et biophysica acta

Published: April 01, 2016

Plasma levels of carboxypeptidase U (CPU, CPB2 or TAFIa) are elevated in patients with acute myocardial infarction.

Plasma levels of carboxypeptidase U (CPU, CPB2 or TAFIa) are elevated in patients with acute myocardial infarction.

Journal: Journal of thrombosis and haemostasis : JTH

Published: April 22, 2015

Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements.

Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements.

Journal: Analytical biochemistry

Published: June 11, 2013

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Last Updated: 09/26/2026