Yaopeng P. Zhao

State Key Lab Of Phytochemistry And Natural Medicines, CAS Dalian 116023 China +86-411-84379539 +86-411-84379519
Dalian, 843795, China

Last Updated: 09/26/2026

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Found 28 publications

Design, synthesis, and characterization of species-independent h/mGPR35 agonists for MAFLD/MASH.

Design, synthesis, and characterization of species-independent h/mGPR35 agonists for MAFLD/MASH.

Journal: Bioorganic chemistry

Published: May 13, 2026

Probe and Assay Dependent Pharmacology of Dantrolene Analogues at the GPR35.

Probe and Assay Dependent Pharmacology of Dantrolene Analogues at the GPR35.

Journal: ACS medicinal chemistry letters

Published: January 28, 2026

Design and synthesis of novel ATP-citrate lyase inhibitors and their effects on MAFLD/MASH.

Design and synthesis of novel ATP-citrate lyase inhibitors and their effects on MAFLD/MASH.

Journal: European journal of medicinal chemistry

Published: December 29, 2025

Gαq activation of free fatty acid receptor 4 suppresses metabolic dysfunction by disrupting Nr1h3-PPARγ axis.

Gαq activation of free fatty acid receptor 4 suppresses metabolic dysfunction by disrupting Nr1h3-PPARγ axis.

Journal: Nature communications

Published: October 15, 2025

β-caryolane derivatives as novel anti-colorectal cancer agents: synthesis and in vitro biological evaluation.

β-caryolane derivatives as novel anti-colorectal cancer agents: synthesis and in vitro biological evaluation.

Journal: RSC advances

Published: September 26, 2025

Uncovering Anticancer Mechanisms of Spiramycin Derivatives Using Transcriptomic and Metabolomic Analyses.

Uncovering Anticancer Mechanisms of Spiramycin Derivatives Using Transcriptomic and Metabolomic Analyses.

Journal: Metabolites

Published: July 22, 2025

Lipidization of gelsemine facilitates its cellular uptake and anti-tumor activity.

Lipidization of gelsemine facilitates its cellular uptake and anti-tumor activity.

Journal: Bioorganic chemistry

Published: June 20, 2025

Design, synthesis and biological evaluation of novel β-caryophyllene derivatives as potential anti-cancer agents through the ROS-mediated apoptosis pathway.

Design, synthesis and biological evaluation of novel β-caryophyllene derivatives as potential anti-cancer agents through the ROS-mediated apoptosis pathway.

Journal: RSC medicinal chemistry

Published: December 03, 2024

Design, semi-synthesis and bioevaluation of koumine-like derivatives as potential antitumor agents in vitro and in vivo.

Design, semi-synthesis and bioevaluation of koumine-like derivatives as potential antitumor agents in vitro and in vivo.

Journal: Future medicinal chemistry

Published: August 27, 2024

Identification and Validation of New DNA-PKcs Inhibitors through High-Throughput Virtual Screening and Experimental Verification.

Identification and Validation of New DNA-PKcs Inhibitors through High-Throughput Virtual Screening and Experimental Verification.

Journal: International journal of molecular sciences

Published: June 07, 2024

Synthesis, anticancer and antibacterial evaluation of novel spiramycin-acylated derivatives.

Synthesis, anticancer and antibacterial evaluation of novel spiramycin-acylated derivatives.

Journal: RSC advances

Published: April 27, 2024

Spatial multi-omics characterizes GPR35-relevant lipid metabolism signatures across liver zonation in MASLD.

Spatial multi-omics characterizes GPR35-relevant lipid metabolism signatures across liver zonation in MASLD.

Journal: Life metabolism

Published: April 22, 2024

Showing 1-12 of 28

Last Updated: 09/26/2026