Yashpal S. Chhonker

Jankipuram Extention Sector 10, Sitapur Road
Lucknow, UP 226031, India

Last Updated: 09/26/2026

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Found 99 publications

Development and Validation of an LC-MS/MS Method for the Quantitation of JNJ-64619178 (JNJ) in Mouse Plasma: Characterization of In Vitro and In Vivo Pharmacokinetic Properties.

Development and Validation of an LC-MS/MS Method for the Quantitation of JNJ-64619178 (JNJ) in Mouse Plasma: Characterization of In Vitro and In Vivo Pharmacokinetic Properties.

Journal: Molecules (Basel, Switzerland)

Published: March 06, 2026

Design, synthesis, and biological evaluation of 2-morpholino-4H-chromen-4-one derivatives as a potent dual PI3K/BRD4 inhibitors.

Design, synthesis, and biological evaluation of 2-morpholino-4H-chromen-4-one derivatives as a potent dual PI3K/BRD4 inhibitors.

Journal: European journal of medicinal chemistry

Published: February 18, 2026

Discovery of a "First-in-Class" Selective Multikinase (CDK4/6/9-AURKA/B) Inhibitor, LCI133, for Neuroblastoma.

Discovery of a "First-in-Class" Selective Multikinase (CDK4/6/9-AURKA/B) Inhibitor, LCI133, for Neuroblastoma.

Journal: Journal of medicinal chemistry

Published: November 06, 2025

Further Structure-Activity Relationship of G Protein-Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds.

Further Structure-Activity Relationship of G Protein-Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds.

Journal: ChemMedChem

Published: January 14, 2025

Impact of fixed phosphorus position on activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.

Impact of fixed phosphorus position on activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: January 10, 2025

Coenzyme Q10 deficiency disrupts lipid metabolism by altering cholesterol homeostasis in neurons.

Coenzyme Q10 deficiency disrupts lipid metabolism by altering cholesterol homeostasis in neurons.

Journal: Free radical biology & medicine

Published: November 25, 2024

Structure-activity relationship of isoprenoid triazole bisphosphonate-based geranylgeranyl diphosphate synthase inhibitors: Effects on pharmacokinetics, biodistribution, and hepatic transporters.

Structure-activity relationship of isoprenoid triazole bisphosphonate-based geranylgeranyl diphosphate synthase inhibitors: Effects on pharmacokinetics, biodistribution, and hepatic transporters.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: October 03, 2024

Antimicrobial peptide developed with machine learning sequence optimization targets drug resistant Staphylococcus aureus in mice.

Antimicrobial peptide developed with machine learning sequence optimization targets drug resistant Staphylococcus aureus in mice.

Journal: The Journal of clinical investigation

Published: August 02, 2024

Development and Validation of an LC-MS/MS Assay for the Quantitation of MO-OH-Nap Tropolone in Mouse Plasma: Application to In Vitro and In Vivo Pharmacokinetic Studies.

Development and Validation of an LC-MS/MS Assay for the Quantitation of MO-OH-Nap Tropolone in Mouse Plasma: Application to In Vitro and In Vivo Pharmacokinetic Studies.

Journal: Molecules (Basel, Switzerland)

Published: July 19, 2024

Geranylgeranyl diphosphate synthase inhibition impairs osteoclast differentiation, morphology, and resorptive activity.

Geranylgeranyl diphosphate synthase inhibition impairs osteoclast differentiation, morphology, and resorptive activity.

Journal: JBMR plus

Published: July 17, 2024

Polymer-Based Drug Delivery Systems for Cancer Therapeutics.

Polymer-Based Drug Delivery Systems for Cancer Therapeutics.

Journal: Polymers

Published: February 14, 2024

Coumarin-Based Aldo-Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors.

Coumarin-Based Aldo-Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors.

Journal: ChemMedChem

Published: January 25, 2024

Showing 1-12 of 99

Last Updated: 09/26/2026