Yasien Sayed

Johannesburg, GT 2000, South Africa

Last Updated: 09/26/2026

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Found 52 publications

Subtype-Specific HIV-1 Protease and the Role of Hinge and Flap Dynamics in Drug Resistance: A Subtype C Narrative.

Subtype-Specific HIV-1 Protease and the Role of Hinge and Flap Dynamics in Drug Resistance: A Subtype C Narrative.

Journal: Viruses

Published: June 06, 2025

The cleavage of indinavir sulfate: synthesis and characterization of a cis-1-amino-2-indanol salt.

The cleavage of indinavir sulfate: synthesis and characterization of a cis-1-amino-2-indanol salt.

Journal: Acta crystallographica. Section C, Structural chemistry

Published: May 05, 2025

Integrative Computational Approaches for Understanding Drug Resistance in HIV-1 Protease Subtype C.

Integrative Computational Approaches for Understanding Drug Resistance in HIV-1 Protease Subtype C.

Journal: Viruses

Published: May 03, 2025

Cytotoxic pyrrole-based gold(III) chelates target human topoisomerase II as dual-mode inhibitors and interact with human serum albumin.

Cytotoxic pyrrole-based gold(III) chelates target human topoisomerase II as dual-mode inhibitors and interact with human serum albumin.

Journal: European journal of medicinal chemistry

Published: December 23, 2024

Purification, Crystallization, and Preliminary X-ray Diffraction Studies on Hemoglobin from the Angora Goat (Capra Aegagrus Hircus).

Purification, Crystallization, and Preliminary X-ray Diffraction Studies on Hemoglobin from the Angora Goat (Capra Aegagrus Hircus).

Journal: Protein and peptide letters

Published: December 04, 2024

Structural and Functional Studies on HIV Protease: Mechanism of Action, Subtypes, Inhibitors, and Drug Resistance.

Structural and Functional Studies on HIV Protease: Mechanism of Action, Subtypes, Inhibitors, and Drug Resistance.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: November 22, 2024

Structural Implications of HIV-1 Protease Subtype C Bound to Darunavir: A Molecular Dynamics Study.

Structural Implications of HIV-1 Protease Subtype C Bound to Darunavir: A Molecular Dynamics Study.

Journal: Proteins

Published: September 03, 2024

Unveiling a Hidden Pocket in HIV-1 Protease: New Insights Into Retroviral Protease Cantilever-Tip Region Characteristics.

Unveiling a Hidden Pocket in HIV-1 Protease: New Insights Into Retroviral Protease Cantilever-Tip Region Characteristics.

Journal: Proteins

Published: April 04, 2024

Exploring the evolutionary trajectory and functional landscape of cannabinoid receptors: A comprehensive bioinformatic analysis.

Exploring the evolutionary trajectory and functional landscape of cannabinoid receptors: A comprehensive bioinformatic analysis.

Journal: Computational biology and chemistry

Published: March 07, 2024

Structural multiplicity in a solvated hydrate of the anti-retroviral protease inhibitor Lopinavir.

Structural multiplicity in a solvated hydrate of the anti-retroviral protease inhibitor Lopinavir.

Journal: Acta crystallographica. Section E, Crystallographic communications

Published: February 12, 2024

Mechanism of drug resistance in HIV-1 protease subtype C in the presence of Atazanavir.

Mechanism of drug resistance in HIV-1 protease subtype C in the presence of Atazanavir.

Journal: Current research in structural biology

Published: December 28, 2023

Contrasting the effect of hinge region insertions and non-active site mutations on HIV protease-inhibitor interactions: Insights from altered flap dynamics.

Contrasting the effect of hinge region insertions and non-active site mutations on HIV protease-inhibitor interactions: Insights from altered flap dynamics.

Journal: Journal of molecular graphics & modelling

Published: October 31, 2023

Showing 1-12 of 52

Last Updated: 09/26/2026