Yasser M. Loksha

Arish, SIN, Egypt

Last Updated: 09/26/2026

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Found 8 publications

Design and synthesis of 1-Phenyl-2-thioaryl-4-benzyl-5-methylimidazoles as dual STAT3/NF-κB inhibitors for triple-negative breast Cancer therapy.

Design and synthesis of 1-Phenyl-2-thioaryl-4-benzyl-5-methylimidazoles as dual STAT3/NF-κB inhibitors for triple-negative breast Cancer therapy.

Journal: Bioorganic chemistry

Published: March 08, 2026

Synthesis of 1,2,4-triazole and 1,3,4-oxadiazole derivatives as inhibitors for STAT3 enzymes of breast cancer.

Synthesis of 1,2,4-triazole and 1,3,4-oxadiazole derivatives as inhibitors for STAT3 enzymes of breast cancer.

Journal: Archiv der Pharmazie

Published: June 27, 2023

Design and synthesis of 2-Substituted-4-benzyl-5-methylimidazoles as new potential Anti-breast cancer agents to inhibit oncogenic STAT3 functions.

Design and synthesis of 2-Substituted-4-benzyl-5-methylimidazoles as new potential Anti-breast cancer agents to inhibit oncogenic STAT3 functions.

Journal: Bioorganic chemistry

Published: January 28, 2021

Synthesis and biological screening of some novel 6-substituted 2-alkylpyridazin-3(2H)-ones as anti-inflammatory and analgesic agents.

Synthesis and biological screening of some novel 6-substituted 2-alkylpyridazin-3(2H)-ones as anti-inflammatory and analgesic agents.

Journal: Archiv der Pharmazie

Published: October 07, 2019

Synthesis of Some Novel 2,6-Disubstituted Pyridazin-3(2H)-one Derivatives as Analgesic, Anti-Inflammatory, and Non-Ulcerogenic Agents.

Synthesis of Some Novel 2,6-Disubstituted Pyridazin-3(2H)-one Derivatives as Analgesic, Anti-Inflammatory, and Non-Ulcerogenic Agents.

Journal: Archiv der Pharmazie

Published: March 19, 2017

Synthesis and Anti-HIV-1 Evaluation of Some Novel MC-1220 Analogs as Non-Nucleoside Reverse Transcriptase Inhibitors.

Synthesis and Anti-HIV-1 Evaluation of Some Novel MC-1220 Analogs as Non-Nucleoside Reverse Transcriptase Inhibitors.

Journal: Archiv der Pharmazie

Published: January 11, 2016

Facile synthesis of the NNRTI microbicide MC-1220 and synthesis of its phosphoramidate prodrugs.

Facile synthesis of the NNRTI microbicide MC-1220 and synthesis of its phosphoramidate prodrugs.

Journal: Organic & biomolecular chemistry

Published: November 27, 2015

Synthesis of novel fluoro analogues of MKC442 as microbicides.

Synthesis of novel fluoro analogues of MKC442 as microbicides.

Journal: Journal of medicinal chemistry

Published: May 09, 2014

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Last Updated: 09/26/2026