Ye Chen

Hangzhou, China

Last Updated: 09/26/2026

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Found 14 publications

Harnessing MDM2-Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma.

Harnessing MDM2-Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: November 14, 2025

Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor Activity.

Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor Activity.

Journal: Journal of medicinal chemistry

Published: October 09, 2025

XPO1 inhibitor KPT-330 disrupts the core transcriptional regulatory circuitry of dedifferentiated liposarcoma by modulating the translation process.

XPO1 inhibitor KPT-330 disrupts the core transcriptional regulatory circuitry of dedifferentiated liposarcoma by modulating the translation process.

Journal: Oncogene

Published: September 09, 2025

Exploiting targeted degradation of cyclins and cyclin-dependent kinases for cancer therapeutics: a review.

Exploiting targeted degradation of cyclins and cyclin-dependent kinases for cancer therapeutics: a review.

Journal: Journal of Zhejiang University. Science. B

Published: August 27, 2025

Driver genomic lesions in MDM2, CDK4, and JUN co-opt targetable super-enhancer networks to impose liposarcomagenic core regulatory circuitry.

Driver genomic lesions in MDM2, CDK4, and JUN co-opt targetable super-enhancer networks to impose liposarcomagenic core regulatory circuitry.

Journal: Journal of advanced research

Published: July 10, 2025

Chronic exposure to environmental concentrations of enrofloxacin impairs neutrophil function in zebrafish via HPT axis disruption and hematopoietic dysregulation.

Chronic exposure to environmental concentrations of enrofloxacin impairs neutrophil function in zebrafish via HPT axis disruption and hematopoietic dysregulation.

Journal: Journal of hazardous materials

Published: April 07, 2025

Targeted therapy for pediatric glioma: RAF(t)ing in the molecular era.

Targeted therapy for pediatric glioma: RAF(t)ing in the molecular era.

Journal: World journal of pediatrics : WJP

Published: June 10, 2024

Polyphyllins in cancer therapy: A systematic review and meta-analysis of animal studies.

Polyphyllins in cancer therapy: A systematic review and meta-analysis of animal studies.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: March 07, 2023

Histological and molecular classifications of pediatric glioma with time-dependent diffusion MRI-based microstructural mapping.

Histological and molecular classifications of pediatric glioma with time-dependent diffusion MRI-based microstructural mapping.

Journal: Neuro-oncology

Published: January 08, 2023

Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities.

Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: December 15, 2021

CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.

CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.

Journal: Cancer letters

Published: January 03, 2018

The role of CXCL12 in tumor microenvironment.

The role of CXCL12 in tumor microenvironment.

Journal: Gene

Published: February 10, 2017

Showing 1-12 of 14

Last Updated: 09/26/2026