Yi Bi

Key Laboratory Of Molecular Pharmacology And Drug Evaluation, Yantai 264005, PR China
Puerto Rico

Last Updated: 09/26/2026

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Found 21 publications

Diversified applications and research progress of plant-derived natural products in PROTAC technology.

Diversified applications and research progress of plant-derived natural products in PROTAC technology.

Journal: Bioorganic chemistry

Published: August 26, 2025

Discovery of novel fusidic acid derivatives in mitigating LPS-induced acute liver injury by modulating RIPK1.

Discovery of novel fusidic acid derivatives in mitigating LPS-induced acute liver injury by modulating RIPK1.

Journal: Bioorganic & medicinal chemistry letters

Published: April 03, 2025

Design and Synthesis of Hederagenin Derivatives for the Treatment of Sepsis by Targeting TAK1 and Regulating the TAK1-NF-κB/MAPK Signaling.

Design and Synthesis of Hederagenin Derivatives for the Treatment of Sepsis by Targeting TAK1 and Regulating the TAK1-NF-κB/MAPK Signaling.

Journal: Journal of medicinal chemistry

Published: January 16, 2025

Discovery and biological evaluation of hederagenin derivatives as non-substrate inhibitors of P-glycoprotein-mediated multidrug resistance.

Discovery and biological evaluation of hederagenin derivatives as non-substrate inhibitors of P-glycoprotein-mediated multidrug resistance.

Journal: European journal of medicinal chemistry

Published: December 03, 2024

Ocotillol Derivatives Mitigate Retinal Ischemia-Reperfusion Injury by Regulating the Keap1/Nrf2/ARE Signaling Pathway.

Ocotillol Derivatives Mitigate Retinal Ischemia-Reperfusion Injury by Regulating the Keap1/Nrf2/ARE Signaling Pathway.

Journal: Journal of medicinal chemistry

Published: August 15, 2024

Discovery of novel ocotillol derivatives modulating glucocorticoid receptor/NF-κB signaling for the treatment of sepsis.

Discovery of novel ocotillol derivatives modulating glucocorticoid receptor/NF-κB signaling for the treatment of sepsis.

Journal: European journal of medicinal chemistry

Published: January 08, 2024

Design and synthesis of novel hederagonic acid analogs as potent anti-inflammatory compounds capable of protecting against LPS-induced acute lung injury.

Design and synthesis of novel hederagonic acid analogs as potent anti-inflammatory compounds capable of protecting against LPS-induced acute lung injury.

Journal: European journal of medicinal chemistry

Published: October 05, 2023

Design and synthesis of hederagenin derivatives modulating STING/NF-κB signaling for the relief of acute liver injury in septic mice.

Design and synthesis of hederagenin derivatives modulating STING/NF-κB signaling for the relief of acute liver injury in septic mice.

Journal: European journal of medicinal chemistry

Published: August 30, 2022

Design, synthesis, and biological evaluation of ocotillol derivatives fused with 2-aminothiazole via A-ring as modulators of P-glycoprotein-mediated multidrug resistance.

Design, synthesis, and biological evaluation of ocotillol derivatives fused with 2-aminothiazole via A-ring as modulators of P-glycoprotein-mediated multidrug resistance.

Journal: European journal of medicinal chemistry

Published: July 31, 2022

Discovery of fusidic acid derivatives as novel STING inhibitors for treatment of sepsis.

Discovery of fusidic acid derivatives as novel STING inhibitors for treatment of sepsis.

Journal: European journal of medicinal chemistry

Published: July 25, 2022

Design, synthesis, and tumor drug resistance reversal activity of novel hederagenin derivatives modified by nitrogen-containing heterocycles.

Design, synthesis, and tumor drug resistance reversal activity of novel hederagenin derivatives modified by nitrogen-containing heterocycles.

Journal: European journal of medicinal chemistry

Published: January 03, 2022

Design, synthesis and antibacterial evaluation of ocotillol derivatives with polycyclic nitrogen-containing groups.

Design, synthesis and antibacterial evaluation of ocotillol derivatives with polycyclic nitrogen-containing groups.

Journal: Future medicinal chemistry

Published: April 30, 2021

Showing 1-12 of 21

Last Updated: 09/26/2026