Yi Guan

Key Laboratory Of Medical Cell Biology, Key Laboratory Of Liaoning Province
Shenyang, 110122, China

Last Updated: 09/26/2026

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Found 9 publications

Enhanced insulin signaling via circulating ATG7: A potential therapeutic strategy for diabetes.

Enhanced insulin signaling via circulating ATG7: A potential therapeutic strategy for diabetes.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 29, 2025

Atg7 senses ATP levels and regulates AKT1-PDCD4 phosphorylation-ubiquitination axis to promote survival during metabolic stress.

Atg7 senses ATP levels and regulates AKT1-PDCD4 phosphorylation-ubiquitination axis to promote survival during metabolic stress.

Journal: Communications biology

Published: June 26, 2023

De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity.

De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity.

Journal: Oncogene

Published: August 12, 2022

Progerin modulates the IGF-1R/Akt signaling involved in aging.

Progerin modulates the IGF-1R/Akt signaling involved in aging.

Journal: Science advances

Published: July 20, 2022

Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.

Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.

Journal: Cell reports

Published: November 17, 2021

The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis.

The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis.

Journal: Science advances

Published: August 29, 2020

ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.

ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.

Journal: The EMBO journal

Published: July 31, 2019

SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylation.

SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylation.

Journal: Cell death and differentiation

Published: November 11, 2018

NF-κB-DICER-miRs Axis Regulates TNF-α Expression in Responses to Endotoxin Stress.

NF-κB-DICER-miRs Axis Regulates TNF-α Expression in Responses to Endotoxin Stress.

Journal: International journal of biological sciences

Published: May 05, 2015

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Last Updated: 09/26/2026