Yi Le

Guiyang, 550025, China

Last Updated: 09/26/2026

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Found 37 publications

An ER-targeted electronic-switched cascade probe for synchronous dual-channel imaging of H2S and HClO during liver fibrosis.

An ER-targeted electronic-switched cascade probe for synchronous dual-channel imaging of H2S and HClO during liver fibrosis.

Journal: Analytica chimica acta

Published: July 21, 2026

Synthesis and mechanistic investigation of N-Alkoxybenzamide derivatives as EGFR inhibitors.

Synthesis and mechanistic investigation of N-Alkoxybenzamide derivatives as EGFR inhibitors.

Journal: Bioorganic chemistry

Published: November 30, 2025

A tri-channel ratiometric fluorescent probe with dual recognition sites for imaging exogenous and endogenous hypochlorite in living cells.

A tri-channel ratiometric fluorescent probe with dual recognition sites for imaging exogenous and endogenous hypochlorite in living cells.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Published: October 15, 2025

Discovery of a macrocyclic FAK inhibitor GZD-257 for treatment of glioblastoma.

Discovery of a macrocyclic FAK inhibitor GZD-257 for treatment of glioblastoma.

Journal: Bioorganic & medicinal chemistry letters

Published: July 12, 2025

A novel fluorescent probe for rapid and selective detection of fluoride ions in living cells.

A novel fluorescent probe for rapid and selective detection of fluoride ions in living cells.

Journal: Analytical methods : advancing methods and applications

Published: January 09, 2025

Engineered nanovesicles targeting SERPINE1 overcome temozolomide resistance in glioblastoma.

Engineered nanovesicles targeting SERPINE1 overcome temozolomide resistance in glioblastoma.

Journal: Cellular signalling

Published: December 06, 2024

Discovery of noncovalent diaminopyrimidine-based Inhibitors for glioblastoma via a dual FAK/DNA targeting strategy.

Discovery of noncovalent diaminopyrimidine-based Inhibitors for glioblastoma via a dual FAK/DNA targeting strategy.

Journal: European journal of medicinal chemistry

Published: October 20, 2024

Development of a novel fluorescent probe for the Selective and sequential imaging of fluoride and hypochlorite.

Development of a novel fluorescent probe for the Selective and sequential imaging of fluoride and hypochlorite.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Published: October 14, 2024

Design, synthesis and antitumor activity of 4-indazolylpyrimidine derivatives as EGFR inhibitors.

Design, synthesis and antitumor activity of 4-indazolylpyrimidine derivatives as EGFR inhibitors.

Journal: Molecular diversity

Published: August 14, 2024

Clusterin-mediated polarization of M2 macrophages: a mechanism of temozolomide resistance in glioblastoma stem cells.

Clusterin-mediated polarization of M2 macrophages: a mechanism of temozolomide resistance in glioblastoma stem cells.

Journal: Stem cell research & therapy

Published: July 29, 2024

A New Phenothiazine-Based Fluorescent Probe for Rapid and Specific Detection of Fluoride.

A New Phenothiazine-Based Fluorescent Probe for Rapid and Specific Detection of Fluoride.

Journal: Journal of fluorescence

Published: May 23, 2024

Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation.

Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation.

Journal: European journal of medicinal chemistry

Published: November 27, 2023

Showing 1-12 of 37

Last Updated: 09/26/2026