Yichao Xu

Key Laboratory Of Advanced Drug Preparation Technologies, Henan Province Key Laboratory Of Small Molecule Drug Discovery And Applied Research, 100 Science Avenue
Zhengzhou, 450001, China

Last Updated: 09/26/2026

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Found 10 publications

Synthesis and identification of a novel selective USP7 degrader that inhibits the migration of upper gastrointestinal cancer cells without affecting proliferation.

Synthesis and identification of a novel selective USP7 degrader that inhibits the migration of upper gastrointestinal cancer cells without affecting proliferation.

Journal: European journal of medicinal chemistry

Published: September 09, 2025

The MLL4: Roles in cell differentiation, adipogenesis and cancer.

The MLL4: Roles in cell differentiation, adipogenesis and cancer.

Journal: Biochemical pharmacology

Published: July 08, 2025

Targeting lysine-specific demethylase 1 inhibits melanoma metastasis via the NF2-Hippo-YAP pathway.

Targeting lysine-specific demethylase 1 inhibits melanoma metastasis via the NF2-Hippo-YAP pathway.

Journal: Cell death & disease

Published: June 26, 2025

PIK3IP1: structure, aberration, function, and regulation in diseases.

PIK3IP1: structure, aberration, function, and regulation in diseases.

Journal: European journal of pharmacology

Published: February 15, 2024

NRG1 promotes tumorigenesis and metastasis and afatinib treatment efficiency is enhanced by NRG1 inhibition in esophageal squamous cell carcinoma.

NRG1 promotes tumorigenesis and metastasis and afatinib treatment efficiency is enhanced by NRG1 inhibition in esophageal squamous cell carcinoma.

Journal: Biochemical pharmacology

Published: October 02, 2023

The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ ratio.

The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ ratio.

Journal: Genes & diseases

Published: September 12, 2023

Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC.

Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC.

Journal: Cell death & disease

Published: March 09, 2023

Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma.

Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma.

Journal: Genes & diseases

Published: May 16, 2022

Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer.

Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer.

Journal: Acta pharmaceutica Sinica. B

Published: March 24, 2021

Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway.

Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway.

Journal: European journal of medicinal chemistry

Published: May 01, 2020

Showing 1-10 of 10

Last Updated: 09/26/2026