Yihui Gu

Shanghai, China

Last Updated: 09/26/2026

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Found 14 publications

Efficacy and Safety of Tunlametinib in Adults with Inoperable Neurofibromatosis Type 1-Associated Plexiform Neurofibromas: Phase IIa Trial and Biomarker Research.

Efficacy and Safety of Tunlametinib in Adults with Inoperable Neurofibromatosis Type 1-Associated Plexiform Neurofibromas: Phase IIa Trial and Biomarker Research.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: September 02, 2025

Cranial Nerve Ganglion Involvement Predicts Malignant Transformation of Plexiform Neurofibromas in Neurofibromatosis Type 1.

Cranial Nerve Ganglion Involvement Predicts Malignant Transformation of Plexiform Neurofibromas in Neurofibromatosis Type 1.

Journal: Plastic and reconstructive surgery

Published: July 17, 2025

Emerging mechanism and therapeutic potential of neurofibromatosis type 1-related nerve system tumor: Advancing insights into tumor development.

Emerging mechanism and therapeutic potential of neurofibromatosis type 1-related nerve system tumor: Advancing insights into tumor development.

Journal: Neuro-oncology advances

Published: March 26, 2025

Reduced PTPRS expression promotes epithelial-mesenchymal transition of Schwann cells in NF1-related plexiform neurofibromas.

Reduced PTPRS expression promotes epithelial-mesenchymal transition of Schwann cells in NF1-related plexiform neurofibromas.

Journal: Cancer letters

Published: April 24, 2024

Genotype-phenotype correlations and treatment innovation of neurofibromatosis type 1 (NF1): Current understanding and perspective.

Genotype-phenotype correlations and treatment innovation of neurofibromatosis type 1 (NF1): Current understanding and perspective.

Journal: Chinese medical journal

Published: December 23, 2023

Genotype-phenotype correlations of neurofibromatosis type 1: a cross-sectional study from a large Chinese cohort.

Genotype-phenotype correlations of neurofibromatosis type 1: a cross-sectional study from a large Chinese cohort.

Journal: Journal of neurology

Published: September 26, 2023

RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST.

RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST.

Journal: Cellular oncology (Dordrecht, Netherlands)

Published: April 18, 2023

Knockdown of NCOR2 Inhibits Cell Proliferation via BDNF/TrkB/ERK in NF1-Derived MPNSTs.

Knockdown of NCOR2 Inhibits Cell Proliferation via BDNF/TrkB/ERK in NF1-Derived MPNSTs.

Journal: Cancers

Published: November 04, 2022

FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner.

FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner.

Journal: Cancer gene therapy

Published: September 22, 2022

Concurrent inhibition of FAK/SRC and MEK overcomes MEK inhibitor resistance in Neurofibromatosis Type I related malignant peripheral nerve sheath tumors.

Concurrent inhibition of FAK/SRC and MEK overcomes MEK inhibitor resistance in Neurofibromatosis Type I related malignant peripheral nerve sheath tumors.

Journal: Frontiers in oncology

Published: April 01, 2022

Preclinical Assessment of MEK Inhibitors for Malignant Peripheral Nerve Sheath Tumors Reveals Differences in Efficacy and Adaptive Response.

Preclinical Assessment of MEK Inhibitors for Malignant Peripheral Nerve Sheath Tumors Reveals Differences in Efficacy and Adaptive Response.

Journal: Frontiers in oncology

Published: March 24, 2022

Photonic hyperthermia of malignant peripheral nerve sheath tumors at the third near-infrared biowindow.

Photonic hyperthermia of malignant peripheral nerve sheath tumors at the third near-infrared biowindow.

Journal: eLife

Published: November 15, 2021

Showing 1-12 of 14

Last Updated: 09/26/2026