Yimin Hua

Jiangsu Key Laboratory For Molecular And Medical Biotechnology
Nanjing, China

Last Updated: 09/26/2026

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Found 24 publications

SMN deficiency inhibits endochondral ossification via promoting TRAF6-induced ubiquitination degradation of YBX1 in spinal muscular atrophy.

SMN deficiency inhibits endochondral ossification via promoting TRAF6-induced ubiquitination degradation of YBX1 in spinal muscular atrophy.

Journal: Bone research

Published: November 24, 2024

Mass photometry as a fast, facile characterization tool for direct measurement of mRNA length.

Mass photometry as a fast, facile characterization tool for direct measurement of mRNA length.

Journal: Biology methods & protocols

Published: November 13, 2024

Antisense-mediated exon skipping targeting EZH2 suppresses tumor growth in a xenograft mouse model of hepatocellular carcinoma.

Antisense-mediated exon skipping targeting EZH2 suppresses tumor growth in a xenograft mouse model of hepatocellular carcinoma.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: July 14, 2024

Whole-transcriptome sequencing in neural and non-neural tissues of a mouse model identifies miR-34a as a key regulator in SMA pathogenesis.

Whole-transcriptome sequencing in neural and non-neural tissues of a mouse model identifies miR-34a as a key regulator in SMA pathogenesis.

Journal: Molecular therapy. Nucleic acids

Published: March 27, 2024

HnRNPR strongly represses splicing of a critical exon associated with spinal muscular atrophy through binding to an exonic AU-rich element.

HnRNPR strongly represses splicing of a critical exon associated with spinal muscular atrophy through binding to an exonic AU-rich element.

Journal: Journal of medical genetics

Published: January 27, 2023

Rescue of mis-splicing of a common SLC26A4 mutant associated with sensorineural hearing loss by antisense oligonucleotides.

Rescue of mis-splicing of a common SLC26A4 mutant associated with sensorineural hearing loss by antisense oligonucleotides.

Journal: Molecular therapy. Nucleic acids

Published: September 12, 2021

Systematic characterization of short intronic splicing-regulatory elements in SMN2 pre-mRNA.

Systematic characterization of short intronic splicing-regulatory elements in SMN2 pre-mRNA.

Journal: Nucleic acids research

Published: May 13, 2021

Identification of SRSF10 as a regulator of SMN2 ISS-N1.

Identification of SRSF10 as a regulator of SMN2 ISS-N1.

Journal: Human mutation

Published: March 26, 2020

Modulation of PDCD1 exon 3 splicing.

Modulation of PDCD1 exon 3 splicing.

Journal: RNA biology

Published: August 24, 2019

Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model.

Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model.

Journal: Nucleic acids research

Published: August 05, 2019

SMN deficiency causes pain hypersensitivity in a mild SMA mouse model through enhancing excitability of nociceptive dorsal root ganglion neurons.

SMN deficiency causes pain hypersensitivity in a mild SMA mouse model through enhancing excitability of nociceptive dorsal root ganglion neurons.

Journal: Scientific reports

Published: October 18, 2018

A severe mouse model of spinal muscular atrophy develops early systemic inflammation.

A severe mouse model of spinal muscular atrophy develops early systemic inflammation.

Journal: Human molecular genetics

Published: June 05, 2018

Showing 1-12 of 24

Last Updated: 09/26/2026