Yinghong Li

State Key Laboratory Of Bioactive Substances And Function Of Natural Medicines, Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 41 publications

Structural Modification of Tranilast against Poxvirus Based on α, β-Unsaturated Acrylamide Covalent Warhead and Confirmation of the Targets and Mode of Action.

Structural Modification of Tranilast against Poxvirus Based on α, β-Unsaturated Acrylamide Covalent Warhead and Confirmation of the Targets and Mode of Action.

Journal: Journal of medicinal chemistry

Published: April 30, 2026

Linking intestinal distribution to pharmacological mechanism: Berberine prevents and treats colorectal cancer by targeting SIGMAR1.

Linking intestinal distribution to pharmacological mechanism: Berberine prevents and treats colorectal cancer by targeting SIGMAR1.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: February 15, 2026

Identification of LAMP2 as the direct target of aloperine derivatives for degrading PD-L1 through the lysosomal pathway based on deep learning model.

Identification of LAMP2 as the direct target of aloperine derivatives for degrading PD-L1 through the lysosomal pathway based on deep learning model.

Journal: Bioorganic chemistry

Published: February 04, 2026

Identification of the target ANTXR1 and covalent acylation mechanism of 8-esterified cycloberberines against cancer.

Identification of the target ANTXR1 and covalent acylation mechanism of 8-esterified cycloberberines against cancer.

Journal: European journal of medicinal chemistry

Published: December 29, 2025

Design and synthesis of protoberberine analogues to alleviate LPS-induced acute lung injury by targeting HCK and blocking the HCK-NLRP3 axis.

Design and synthesis of protoberberine analogues to alleviate LPS-induced acute lung injury by targeting HCK and blocking the HCK-NLRP3 axis.

Journal: European journal of medicinal chemistry

Published: July 17, 2025

Evolution of 8-esterified cycloberberines as a novel class of antibacterial agents against MDR gram-positive strains by targeting DNA polymerase IIIC.

Evolution of 8-esterified cycloberberines as a novel class of antibacterial agents against MDR gram-positive strains by targeting DNA polymerase IIIC.

Journal: Bioorganic chemistry

Published: February 25, 2025

A dual-view deep learning-driven discovery of cinnamoyl anthranilic acid derivatives against orthopoxvirus through targeting host ITGB3.

A dual-view deep learning-driven discovery of cinnamoyl anthranilic acid derivatives against orthopoxvirus through targeting host ITGB3.

Journal: European journal of medicinal chemistry

Published: January 16, 2025

Pyrylium derivatives as outer membrane permeabilizers against MDR gram-negative bacteria via multi-target mode of action.

Pyrylium derivatives as outer membrane permeabilizers against MDR gram-negative bacteria via multi-target mode of action.

Journal: European journal of medicinal chemistry

Published: January 02, 2025

Synthesis and evolution of 16-membered macrolide carrimycin derivatives as a novel class of anti-HCoV-OC43 agents targeting viral FSE RNA.

Synthesis and evolution of 16-membered macrolide carrimycin derivatives as a novel class of anti-HCoV-OC43 agents targeting viral FSE RNA.

Journal: European journal of medicinal chemistry

Published: December 23, 2024

Lycorine esters exert anti-HCoV-OC43 effect through reversibly acylating cysteine residue in the nsp 12 NiRAN domain.

Lycorine esters exert anti-HCoV-OC43 effect through reversibly acylating cysteine residue in the nsp 12 NiRAN domain.

Journal: Bioorganic chemistry

Published: September 20, 2024

Erratum: Author correction to 'Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects' [Acta Pharmaceutica Sinica B 13 (2023) 2138-2151].

Erratum: Author correction to 'Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects' [Acta Pharmaceutica Sinica B 13 (2023) 2138-2151].

Journal: Acta pharmaceutica Sinica. B

Published: March 15, 2024

Discovery and development of novel 10,12-disubstituted aloperine derivatives against HCoV-OC43 by targeting allosteric site of host TMPRSS2.

Discovery and development of novel 10,12-disubstituted aloperine derivatives against HCoV-OC43 by targeting allosteric site of host TMPRSS2.

Journal: Bioorganic chemistry

Published: February 09, 2024

Showing 1-12 of 41

Last Updated: 09/26/2026