Yiqian Xie

1670 Zhangheng Road, Zhangjiang High Tech Park
Zhangjiang, 201203, China

Last Updated: 09/26/2026

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Found 11 publications

PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma.

PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma.

Journal: Theranostics

Published: November 21, 2019

Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening.

Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening.

Journal: RSC advances

Published: December 07, 2018

Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.

Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.

Journal: Oncogenesis

Published: March 06, 2018

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

Journal: Organic & biomolecular chemistry

Published: November 01, 2017

Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.

Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.

Journal: Journal of medicinal chemistry

Published: October 12, 2017

Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay.

Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay.

Journal: MedChemComm

Published: February 20, 2017

Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.

Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.

Journal: Bioorganic & medicinal chemistry letters

Published: January 04, 2017

Identification of Novel Inhibitors against Coactivator Associated Arginine Methyltransferase 1 Based on Virtual Screening and Biological Assays.

Identification of Novel Inhibitors against Coactivator Associated Arginine Methyltransferase 1 Based on Virtual Screening and Biological Assays.

Journal: BioMed research international

Published: August 02, 2016

Molecular Mechanism underlying PRMT1 Dimerization for SAM Binding and Methylase Activity.

Molecular Mechanism underlying PRMT1 Dimerization for SAM Binding and Methylase Activity.

Journal: Journal of chemical information and modeling

Published: November 13, 2015

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.

Journal: Journal of medicinal chemistry

Published: September 22, 2015

Discovery of two aminoglycoside antibiotics as inhibitors targeting the menin-mixed lineage leukaemia interface.

Discovery of two aminoglycoside antibiotics as inhibitors targeting the menin-mixed lineage leukaemia interface.

Journal: Bioorganic & medicinal chemistry letters

Published: December 26, 2013

Showing 1-11 of 11

Last Updated: 09/26/2026