Yixin Cen

1200 Cailun Road
Shanghai, 201203, China

Last Updated: 09/26/2026

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Found 12 publications

Structure-Based Design and Optimization of Novel PHGDH Inhibitors for Overcoming Erlotinib-Resistant Lung Cancer.

Structure-Based Design and Optimization of Novel PHGDH Inhibitors for Overcoming Erlotinib-Resistant Lung Cancer.

Journal: Journal of medicinal chemistry

Published: June 09, 2026

Maternal plasma microRNA signatures for early detection of early-onset preeclampsia.

Maternal plasma microRNA signatures for early detection of early-onset preeclampsia.

Journal: International journal of biological macromolecules

Published: November 27, 2024

Discovery of natural catechol derivatives as covalent SARS-CoV-2 3CLpro inhibitors.

Discovery of natural catechol derivatives as covalent SARS-CoV-2 3CLpro inhibitors.

Journal: International journal of biological macromolecules

Published: December 27, 2023

Systemic whole transcriptome analysis identified underlying molecular characteristics and regulatory networks implicated in the retina following optic nerve injury.

Systemic whole transcriptome analysis identified underlying molecular characteristics and regulatory networks implicated in the retina following optic nerve injury.

Journal: Experimental eye research

Published: November 11, 2023

Nature-inspired catalytic asymmetric rearrangement of cyclopropylcarbinyl cation.

Nature-inspired catalytic asymmetric rearrangement of cyclopropylcarbinyl cation.

Journal: Science advances

Published: May 10, 2023

Reply to Correspondence on "Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1''.

Reply to Correspondence on "Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1''.

Journal: Angewandte Chemie (International ed. in English)

Published: May 03, 2023

Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy.

Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy.

Journal: Journal of medicinal chemistry

Published: January 03, 2023

Single-cell characterization of macrophages in uveal melanoma uncovers transcriptionally heterogeneous subsets conferring poor prognosis and aggressive behavior.

Single-cell characterization of macrophages in uveal melanoma uncovers transcriptionally heterogeneous subsets conferring poor prognosis and aggressive behavior.

Journal: Experimental & molecular medicine

Published: September 09, 2022

Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1.

Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1.

Journal: Angewandte Chemie (International ed. in English)

Published: September 07, 2021

"Top" or "bottom" switches of a cyclohexanone monooxygenase controlling the enantioselectivity of the sandwiched substrate.

"Top" or "bottom" switches of a cyclohexanone monooxygenase controlling the enantioselectivity of the sandwiched substrate.

Journal: Chemical communications (Cambridge, England)

Published: February 01, 2019

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.

Journal: Nature communications

Published: December 18, 2018

Antitumor gemcitabine conjugated micelles from amphiphilic comb-like random copolymers.

Antitumor gemcitabine conjugated micelles from amphiphilic comb-like random copolymers.

Journal: Colloids and surfaces. B, Biointerfaces

Published: April 09, 2016

Showing 1-12 of 12

Last Updated: 09/26/2026