Yixing Wu

London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 8 publications

Age-related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome.

Age-related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: October 28, 2025

Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models.

Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models.

Journal: PloS one

Published: April 16, 2024

Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B.

Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B.

Journal: Acta neuropathologica communications

Published: June 20, 2023

Editorial: New insights into the role of neuroinflammation and glial cells in the development of neurological disorders.

Editorial: New insights into the role of neuroinflammation and glial cells in the development of neurological disorders.

Journal: Frontiers in cellular neuroscience

Published: February 20, 2023

Cell models for Down syndrome-Alzheimer's disease research.

Cell models for Down syndrome-Alzheimer's disease research.

Journal: Neuronal signaling

Published: October 27, 2021

The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model.

The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model.

Journal: PloS one

Published: November 05, 2020

The antioxidant protein Oxr1 influences aspects of mitochondrial morphology.

The antioxidant protein Oxr1 influences aspects of mitochondrial morphology.

Journal: Free radical biology & medicine

Published: December 08, 2015

Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.

Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.

Journal: Human molecular genetics

Published: January 21, 2015

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Last Updated: 09/26/2026