Yizhen Yin

Jinan, 250101, China

Last Updated: 09/26/2026

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Found 22 publications

A Multi-Channel Machine Learning Model for Predicting the Bioactivity Potential of Macrocyclic Peptides.

A Multi-Channel Machine Learning Model for Predicting the Bioactivity Potential of Macrocyclic Peptides.

Journal: Journal of medicinal chemistry
Published: January 02, 2026

Asymmetric Electrooxidation of Indoles: Mechanistic Insights from an Enantioselective Bromoradical Addition Pathway.

Asymmetric Electrooxidation of Indoles: Mechanistic Insights from an Enantioselective Bromoradical Addition Pathway.

Journal: Organic letters
Published: December 06, 2025

De Novo Discovery of a Macrocyclic Peptide Antagonist of Interleukin-11 with Antirenal Fibrotic Efficacy.

De Novo Discovery of a Macrocyclic Peptide Antagonist of Interleukin-11 with Antirenal Fibrotic Efficacy.

Journal: Journal of medicinal chemistry
Published: September 18, 2025

Ribosomal incorporation of N-acetyl-3,5-bis(chloromethyl)benzylthio-L-alanine for developing an mRNA-displayed bicyclic peptide library cyclized via 1,3,5-tris(methyl)benzene.

Ribosomal incorporation of N-acetyl-3,5-bis(chloromethyl)benzylthio-L-alanine for developing an mRNA-displayed bicyclic peptide library cyclized via 1,3,5-tris(methyl)benzene.

Journal: Organic & biomolecular chemistry
Published: May 27, 2025

De novo discovery of a molecular glue-like macrocyclic peptide that induces MCL1 homodimerization.

De novo discovery of a molecular glue-like macrocyclic peptide that induces MCL1 homodimerization.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 25, 2025

A case of ascending aorta mycotic aneurysm with purulent pericarditis in children

A case of ascending aorta mycotic aneurysm with purulent pericarditis in children

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics
Published: February 20, 2025

Intranasal administration of broad-spectrum macrocyclic peptide inhibitor protects against SARS-CoV-2 Omicron variants.

Intranasal administration of broad-spectrum macrocyclic peptide inhibitor protects against SARS-CoV-2 Omicron variants.

Journal: Nature communications
Published: January 23, 2025

A human-STING specific macrocyclic peptide suppresses cGAS-STING-induced inflammation.

A human-STING specific macrocyclic peptide suppresses cGAS-STING-induced inflammation.

Journal: Annals of the rheumatic diseases
Published: December 14, 2024

De Novo Discovery of a Noncovalent Cell-Penetrating Bicyclic Peptide Inhibitor Targeting SARS-CoV-2 Main Protease.

De Novo Discovery of a Noncovalent Cell-Penetrating Bicyclic Peptide Inhibitor Targeting SARS-CoV-2 Main Protease.

Journal: Journal of medicinal chemistry
Published: November 18, 2024

Ribosomal translation of fluorinated non-canonical amino acids for de novo biologically active fluorinated macrocyclic peptides.

Ribosomal translation of fluorinated non-canonical amino acids for de novo biologically active fluorinated macrocyclic peptides.

Journal: Chemical science
Published: June 20, 2024

Ribosomal Incorporation of Lithocholic Acid into Peptides for the De Novo Discovery Of Peptide-Lithocholic Acid Hybrid Macrocyclic Peptides.

Ribosomal Incorporation of Lithocholic Acid into Peptides for the De Novo Discovery Of Peptide-Lithocholic Acid Hybrid Macrocyclic Peptides.

Journal: ACS chemical biology
Published: June 20, 2024

PepExplainer: An explainable deep learning model for selection-based macrocyclic peptide bioactivity prediction and optimization.

PepExplainer: An explainable deep learning model for selection-based macrocyclic peptide bioactivity prediction and optimization.

Journal: European journal of medicinal chemistry
Published: April 17, 2024
Showing 1-12 of 22

Last Updated: 09/26/2026