Yoan Machado
Vancouver, BC, Canada
Last Updated: 09/26/2026
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Found 18 publications
SARS-CoV-2 3CLpro (main protease) regulates caspase activation of gasdermin-D/E pores leading to secretion and extracellular activity of 3CLpro.
Journal: Cell reports
Published: June 13, 2024
Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CLpro main protease (Mpro) from proteomic identification of P6-P6' active site specificity.
Journal: Journal of virology
Published: May 14, 2024
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.
Journal: Cell reports
Published: July 09, 2021
Enzymatically releasable polyethylene glycol - host defense peptide conjugates with improved activity and biocompatibility.
Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: April 20, 2021
Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage.
Journal: The Journal of biological chemistry
Published: August 02, 2019
Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase.
Journal: The Journal of biological chemistry
Published: May 30, 2019
TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice.
Journal: Allergy
Published: April 25, 2019
Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma.
Journal: The Journal of endocrinology
Published: September 25, 2018
Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.
Journal: Scientific reports
Published: January 12, 2018
Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity.
Journal: Allergy
Published: August 24, 2017
Last Updated: 09/26/2026