Yohei Iguchi

Nagoya, Japan

Last Updated: 09/26/2026

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Found 46 publications

Human iPSC-derived motor neurons as a platform for elucidating TDP-43-related amyotrophic lateral sclerosis pathogenesis: a mini review.

Human iPSC-derived motor neurons as a platform for elucidating TDP-43-related amyotrophic lateral sclerosis pathogenesis: a mini review.

Journal: Frontiers in molecular neuroscience
Published: April 25, 2026

Neuronal TDP-43 regulates myelin formation via neurexin 1 mRNA stabilization.

Neuronal TDP-43 regulates myelin formation via neurexin 1 mRNA stabilization.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 25, 2026

A Family with Patients Manifesting Different Phenotypes of Neuromuscular Disease Depending on the CGG Repeat Number in LRP12.

A Family with Patients Manifesting Different Phenotypes of Neuromuscular Disease Depending on the CGG Repeat Number in LRP12.

Journal: Internal medicine (Tokyo, Japan)
Published: October 22, 2025

The TDP-43I383V heterozygous mutation results in increased TDP-43 expression and altered neuronal activity in ALS patient-derived iPSC motor neurons.

The TDP-43I383V heterozygous mutation results in increased TDP-43 expression and altered neuronal activity in ALS patient-derived iPSC motor neurons.

Journal: Neuroscience research
Published: October 08, 2025

Fatty acid amide hydrolase inhibition for treatment of amyotrophic lateral sclerosis.

Fatty acid amide hydrolase inhibition for treatment of amyotrophic lateral sclerosis.

Journal: JCI insight
Published: August 11, 2025

Downregulation of NEAT1 due to loss of TDP-43 function exacerbates motor neuron degeneration in amyotrophic lateral sclerosis.

Downregulation of NEAT1 due to loss of TDP-43 function exacerbates motor neuron degeneration in amyotrophic lateral sclerosis.

Journal: Brain communications
Published: February 05, 2025

Truncation mutation of CHMP2B disrupts late endosome function but reduces TDP-43 aggregation through HSP70 upregulation.

Truncation mutation of CHMP2B disrupts late endosome function but reduces TDP-43 aggregation through HSP70 upregulation.

Journal: Neurochemistry international
Published: January 12, 2025

Absence of the axon initial segment in sensory neuron enhances resistance to amyotrophic lateral sclerosis.

Absence of the axon initial segment in sensory neuron enhances resistance to amyotrophic lateral sclerosis.

Journal: Brain : a journal of neurology
Published: December 20, 2024

Current Status of Drug Development for Amyotrophic Lateral Sclerosis

Current Status of Drug Development for Amyotrophic Lateral Sclerosis

Journal: Brain and nerve = Shinkei kenkyu no shinpo
Published: November 11, 2024

Dysregulated synaptic gene expression in oligodendrocytes of spinal and bulbar muscular atrophy.

Dysregulated synaptic gene expression in oligodendrocytes of spinal and bulbar muscular atrophy.

Journal: JCI insight
Published: April 22, 2024

Reliability and consistency of the Japanese version of the Primary Lateral Sclerosis Functional Rating Scale.

Reliability and consistency of the Japanese version of the Primary Lateral Sclerosis Functional Rating Scale.

Journal: BMC neurology
Published: April 20, 2024

Dual-modified antisense oligonucleotides targeting oncogenic protocadherin to treat gastric cancer.

Dual-modified antisense oligonucleotides targeting oncogenic protocadherin to treat gastric cancer.

Journal: British journal of cancer
Published: March 18, 2024
Showing 1-12 of 46

Last Updated: 09/26/2026