Yohei Kosugi

Fujisawa, 2518555, Japan

Last Updated: 09/26/2026

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Found 38 publications

Developing Predictive Models by Sharing Predictions - An Investigation of a Federated Learning Approach for ADMET Predictions.

Developing Predictive Models by Sharing Predictions - An Investigation of a Federated Learning Approach for ADMET Predictions.

Journal: Journal of medicinal chemistry

Published: May 29, 2026

Advances in In silico predictive models for DDI prediction: Implications and practical applications in drug discovery.

Advances in In silico predictive models for DDI prediction: Implications and practical applications in drug discovery.

Journal: Drug metabolism and pharmacokinetics

Published: November 05, 2025

Discovery of Pyrazole-Based Positron Emission Tomography Agent that Maps Histone Deacetylase 6 (HDAC6) in the Nonhuman Primate Brain.

Discovery of Pyrazole-Based Positron Emission Tomography Agent that Maps Histone Deacetylase 6 (HDAC6) in the Nonhuman Primate Brain.

Journal: Journal of medicinal chemistry

Published: October 21, 2025

Preclinical characterization of pharmacokinetics, enzyme occupancy, and pharmacodynamics of soticlestat (TAK-935), a novel cholesterol 24-hydroxylase inhibitor.

Preclinical characterization of pharmacokinetics, enzyme occupancy, and pharmacodynamics of soticlestat (TAK-935), a novel cholesterol 24-hydroxylase inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics

Published: September 30, 2025

Characterization of a humanized mouse model of Charcot-Marie-Tooth type 1A for the discovery of human PMP22-targeting drugs.

Characterization of a humanized mouse model of Charcot-Marie-Tooth type 1A for the discovery of human PMP22-targeting drugs.

Journal: Frontiers in neurology

Published: July 02, 2025

Multi-Omics Analysis of Hippocampus in Rats Administered Trimethyltin Chloride.

Multi-Omics Analysis of Hippocampus in Rats Administered Trimethyltin Chloride.

Journal: Neurotoxicity research

Published: January 07, 2025

Ensemble Machine Learning Approaches Based on Molecular Descriptors and Graph Convolutional Networks for Predicting the Efflux Activities of MDR1 and BCRP Transporters.

Ensemble Machine Learning Approaches Based on Molecular Descriptors and Graph Convolutional Networks for Predicting the Efflux Activities of MDR1 and BCRP Transporters.

Journal: The AAPS journal

Published: July 04, 2023

Human Brain Penetration Prediction Using Scaling Approach from Animal Machine Learning Models.

Human Brain Penetration Prediction Using Scaling Approach from Animal Machine Learning Models.

Journal: The AAPS journal

Published: April 26, 2023

Quantitation and characterization of glucosylsphingosine in cerebrospinal fluid (CSF), plasma, and brain of monkey model with Gaucher disease.

Quantitation and characterization of glucosylsphingosine in cerebrospinal fluid (CSF), plasma, and brain of monkey model with Gaucher disease.

Journal: Drug metabolism and pharmacokinetics

Published: February 10, 2023

Highly-sensitive simultaneous quantitation of glucosylsphingosine and galactosylsphingosine in human cerebrospinal fluid by liquid chromatography/tandem mass spectrometry.

Highly-sensitive simultaneous quantitation of glucosylsphingosine and galactosylsphingosine in human cerebrospinal fluid by liquid chromatography/tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis

Published: April 02, 2022

Quantitative assessment of coat-hanger ribs detected on three-dimensional ultrasound for prenatal diagnosis of Kagami-Ogata syndrome.

Quantitative assessment of coat-hanger ribs detected on three-dimensional ultrasound for prenatal diagnosis of Kagami-Ogata syndrome.

Journal: The journal of obstetrics and gynaecology research

Published: October 03, 2021

Author Correction: Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement.

Author Correction: Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement.

Journal: Scientific reports

Published: July 22, 2021

Showing 1-12 of 38

Last Updated: 09/26/2026