Yong S. Cho

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 39 publications

Stereoselective synthesis of 1,6-diazecanes by a tandem aza-Prins type dimerization and cyclization process.

Stereoselective synthesis of 1,6-diazecanes by a tandem aza-Prins type dimerization and cyclization process.

Journal: Chemical communications (Cambridge, England)
Published: December 07, 2022

Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.

Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.

Journal: Journal of enzyme inhibition and medicinal chemistry
Published: March 27, 2021

Construction of 8-Azabicyclo[3.2.1]octanes via Sequential DDQ-Mediated Oxidative Mannich Reactions of N-Aryl Pyrrolidines.

Construction of 8-Azabicyclo[3.2.1]octanes via Sequential DDQ-Mediated Oxidative Mannich Reactions of N-Aryl Pyrrolidines.

Journal: Organic letters
Published: January 31, 2018

Identification of Optically Active Pyrimidine Derivatives as Selective 5-HT2C Modulators.

Identification of Optically Active Pyrimidine Derivatives as Selective 5-HT2C Modulators.

Journal: Molecules (Basel, Switzerland)
Published: July 31, 2017

A Potential PET Radiotracer for the 5-HT2C Receptor: Synthesis and in Vivo Evaluation of 4-(3-[18F]fluorophenethoxy)pyrimidine.

A Potential PET Radiotracer for the 5-HT2C Receptor: Synthesis and in Vivo Evaluation of 4-(3-[18F]fluorophenethoxy)pyrimidine.

Journal: ACS chemical neuroscience
Published: February 15, 2017

Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.

Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.

Journal: Chemical biology & drug design
Published: December 30, 2015

Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists.

Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists.

Journal: Bioorganic & medicinal chemistry letters
Published: September 19, 2015

Crystal structure of (E)-5,5-dimethyl-2-[3-(4-nitro-phen-yl)allyl-idene]cyclo-hexane-1,3-dione.

Crystal structure of (E)-5,5-dimethyl-2-[3-(4-nitro-phen-yl)allyl-idene]cyclo-hexane-1,3-dione.

Journal: Acta crystallographica. Section E, Crystallographic communications
Published: May 30, 2015

Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4 + 3] Cycloaddition/SmI2-Pinacol Coupling.

Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4 + 3] Cycloaddition/SmI2-Pinacol Coupling.

Journal: Organic letters
Published: May 22, 2015

Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach.

Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach.

Journal: Chemical biology & drug design
Published: April 13, 2015

Tubulin inhibitor identification by bioactive conformation alignment pharmacophore-guided virtual screening.

Tubulin inhibitor identification by bioactive conformation alignment pharmacophore-guided virtual screening.

Journal: Chemical biology & drug design
Published: January 21, 2015

Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers.

Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers.

Journal: Organic & biomolecular chemistry
Published: October 29, 2014
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Last Updated: 09/26/2026