Yonglong Zhang

1630 Dongfang Road
Dongfang, 200127, China

Last Updated: 09/26/2026

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Found 18 publications

Cyclin K condensates bridge CDK12 to phosphorylate and drive oncogenic YAP activation in hepatocellular carcinoma.

Cyclin K condensates bridge CDK12 to phosphorylate and drive oncogenic YAP activation in hepatocellular carcinoma.

Journal: Science advances
Published: July 03, 2026

Protein arginine methyltransferase 6 enhances immune checkpoint blockade efficacy via the STING pathway in MMR-proficient colorectal cancer.

Protein arginine methyltransferase 6 enhances immune checkpoint blockade efficacy via the STING pathway in MMR-proficient colorectal cancer.

Journal: Journal for immunotherapy of cancer
Published: February 26, 2025

Noncanonical PI3Kγ signaling addiction is a therapeutic target in a subset of leukemias.

Noncanonical PI3Kγ signaling addiction is a therapeutic target in a subset of leukemias.

Journal: Innovation (Cambridge (Mass.))
Published: July 01, 2024

CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.

CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.

Journal: Cancer letters
Published: March 21, 2024

Histone methyltransferase KMT5C drives liver cancer progression and directs therapeutic response to PARP inhibitors.

Histone methyltransferase KMT5C drives liver cancer progression and directs therapeutic response to PARP inhibitors.

Journal: Hepatology (Baltimore, Md.)
Published: January 20, 2023

Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling.

Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling.

Journal: Theranostics
Published: June 08, 2022

GSTM3 deficiency impedes DNA mismatch repair to promote gastric tumorigenesis via CAND1/NRF2-KEAP1 signaling.

GSTM3 deficiency impedes DNA mismatch repair to promote gastric tumorigenesis via CAND1/NRF2-KEAP1 signaling.

Journal: Cancer letters
Published: January 24, 2022

AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis.

AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis.

Journal: Nature communications
Published: July 12, 2021

Liver organoid as a 3D in vitro model for drug validation and toxicity assessment.

Liver organoid as a 3D in vitro model for drug validation and toxicity assessment.

Journal: Pharmacological research
Published: December 26, 2020

C24-Ceramide Drives Gallbladder Cancer Progression Through Directly Targeting Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Gamma to Facilitate Mammalian Target of Rapamycin Signaling Activation.

C24-Ceramide Drives Gallbladder Cancer Progression Through Directly Targeting Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Gamma to Facilitate Mammalian Target of Rapamycin Signaling Activation.

Journal: Hepatology (Baltimore, Md.)
Published: December 16, 2019

A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis.

A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis.

Journal: Cell reports
Published: November 10, 2019

Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response.

Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response.

Journal: Cell cycle (Georgetown, Tex.)
Published: October 11, 2019
Showing 1-12 of 18

Last Updated: 09/26/2026