Yongsong Tian
Copenhagen, 2100, Denmark
Last Updated: 09/26/2026
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Found 8 publications
Structure-Based Virtual Screening Identifies 2-Arylthiazole-4-Carboxylic Acids as a Novel Class of Nanomolar Affinity Ligands for the CaMKIIα Hub Domain.
Journal: Journal of medicinal chemistry
Published: January 28, 2025
Design, Synthesis, and Pharmacological Evaluation of Nonsteroidal Tricyclic Ligands as Modulators of GABAA Receptors.
Journal: Journal of medicinal chemistry
Published: January 14, 2025
Allosteric factors in the calcium/calmodulin-responsive kinase II hub domain determine selectivity of GHB ligands for CaMKIIα.
Journal: The Journal of biological chemistry
Published: October 25, 2024
CaMKIIα hub ligands are unable to reverse known phenotypes in Angelman syndrome mice.
Journal: Basic & clinical pharmacology & toxicology
Published: September 05, 2024
Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain.
Journal: Journal of medicinal chemistry
Published: November 08, 2022
Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain.
Journal: Journal of medicinal chemistry
Published: May 02, 2022
Discovery of 2-(Imidazo[1,2- b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites.
Journal: Journal of medicinal chemistry
Published: February 15, 2019
Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs.
Journal: Journal of medicinal chemistry
Published: October 14, 2017
Showing 1-8 of 8
Last Updated: 09/26/2026