Yoshihisa Hagihara
Ikeda, 5638577, Japan
Last Updated: 09/26/2026
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Found 78 publications
Replacement of non-canonical interloop disulfide bond of alpaca VHH by hydrophobic amino acids.
Journal: Journal of biochemistry
Published: February 19, 2026
Optimization of antibody binding by adjusting thermodynamic stability during the maturation of antibody affinities.
Journal: Protein science : a publication of the Protein Society
Published: January 07, 2026
Prediction of antigen-responding VHH antibodies by tracking the evolution of antibody along the time course of immunization.
Journal: Frontiers in immunology
Published: November 09, 2023
Quantitative understanding of HepaRG cells during drug-induced intrahepatic cholestasis through changes in bile canaliculi dynamics.
Journal: Pharmacology research & perspectives
Published: February 22, 2022
Stress-activated leukocyte 12/15-lipoxygenase metabolite enhances struggle behaviour and tocotrienols relieve stress-induced behaviour alteration.
Journal: Free radical biology & medicine
Published: May 12, 2021
Tight junction stabilization prevents HepaRG cell death in drug-induced intrahepatic cholestasis.
Journal: Biology open
Published: January 25, 2021
Immune response with long-term memory triggered by amorphous aggregates of misfolded anti-EGFR VHH-7D12 is directed against the native VHH-7D12 as well as the framework of the analogous VHH-9G8.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Published: January 14, 2021
Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion.
Journal: eLife
Published: January 07, 2021
Breakdown of supersaturation barrier links protein folding to amyloid formation.
Journal: Communications biology
Published: July 14, 2020
Switching of cell fate through the regulation of cell growth during drug-induced intrahepatic cholestasis.
Journal: Journal of bioscience and bioengineering
Published: April 09, 2020
Last Updated: 09/26/2026