Yoshihisa Hirota

Saitama, Japan

Last Updated: 09/26/2026

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Found 33 publications

Polypharmacologic phosphoinositide modulation by FTY720 triggers endomembrane trafficking collapse and metabolic starvation in cancer cells.

Polypharmacologic phosphoinositide modulation by FTY720 triggers endomembrane trafficking collapse and metabolic starvation in cancer cells.

Journal: Biochemical and biophysical research communications

Published: March 05, 2026

A new metabolic path in type 3 rickets.

A new metabolic path in type 3 rickets.

Journal: The FEBS journal

Published: December 05, 2025

A New Class of Vitamin K Analogues Containing the Side Chain of Retinoic Acid Have Enhanced Activity for Inducing Neuronal Differentiation.

A New Class of Vitamin K Analogues Containing the Side Chain of Retinoic Acid Have Enhanced Activity for Inducing Neuronal Differentiation.

Journal: ACS chemical neuroscience

Published: July 03, 2025

Divergent roles of 25-hydroxyvitamin D3 and 1α,25-dihydroxyvitamin D3 in neural fate determination: A CYP27B1-dependent neuron formation and VDR-dependent astrocyte development.

Divergent roles of 25-hydroxyvitamin D3 and 1α,25-dihydroxyvitamin D3 in neural fate determination: A CYP27B1-dependent neuron formation and VDR-dependent astrocyte development.

Journal: Biochemical and biophysical research communications

Published: February 19, 2025

Potential of fat-soluble vitamins as a platform for antiviral drug development.

Potential of fat-soluble vitamins as a platform for antiviral drug development.

Journal: Bioorganic & medicinal chemistry letters

Published: January 03, 2025

Azolato-Bridged Dinuclear Platinum(II) Complexes Exhibit Androgen Receptor-Mediated Anti-Prostate Cancer Activity.

Azolato-Bridged Dinuclear Platinum(II) Complexes Exhibit Androgen Receptor-Mediated Anti-Prostate Cancer Activity.

Journal: Inorganic chemistry

Published: September 11, 2024

A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion.

A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion.

Journal: Biochemical and biophysical research communications

Published: April 09, 2024

PI5P4K inhibitors: promising opportunities and challenges.

PI5P4K inhibitors: promising opportunities and challenges.

Journal: The FEBS journal

Published: March 02, 2024

Exploring 2-methyl-substituted vitamin K3 derivatives with potent inhibitory activity against the 3CL protease of SARS-CoV-2.

Exploring 2-methyl-substituted vitamin K3 derivatives with potent inhibitory activity against the 3CL protease of SARS-CoV-2.

Journal: Bioorganic & medicinal chemistry letters

Published: December 30, 2023

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells.

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells.

Journal: Biochemical and biophysical research communications

Published: August 06, 2023

Synthesis of new vitamin K derivatives with a ketone group at the C-1' position of the side chain and their conversion to menaquinone-4.

Synthesis of new vitamin K derivatives with a ketone group at the C-1' position of the side chain and their conversion to menaquinone-4.

Journal: Journal of molecular structure

Published: March 15, 2023

Elucidation of Physiological Functions of Vitamin K in the Brain and Development of New Derivatives for Neuroregeneration

Elucidation of Physiological Functions of Vitamin K in the Brain and Development of New Derivatives for Neuroregeneration

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Published: March 01, 2023

Showing 1-12 of 33

Last Updated: 09/26/2026