Youcef Mehellou

Cardiff, WLS CF103NB, United Kingdom

Last Updated: 09/26/2026

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Found 34 publications

Oxidative Stress-Responsive 1 Kinase Catalytic Activity Promotes Triple Negative Breast Cancer Oncogenic Potential.

Oxidative Stress-Responsive 1 Kinase Catalytic Activity Promotes Triple Negative Breast Cancer Oncogenic Potential.

Journal: ACS pharmacology & translational science

Published: October 14, 2024

Phosphonodiamidate prodrugs of phosphoantigens (ProPAgens) exhibit potent Vγ9/Vδ2 T cell activation and eradication of cancer cells.

Phosphonodiamidate prodrugs of phosphoantigens (ProPAgens) exhibit potent Vγ9/Vδ2 T cell activation and eradication of cancer cells.

Journal: RSC medicinal chemistry

Published: March 26, 2024

PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage.

PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage.

Journal: Journal of medicinal chemistry

Published: May 30, 2023

Parkinson's Disease: Are PINK1 Activators Inching Closer to the Clinic?

Parkinson's Disease: Are PINK1 Activators Inching Closer to the Clinic?

Journal: ACS medicinal chemistry letters

Published: March 01, 2023

Aryloxy Pivaloyloxymethyl Prodrugs as Nucleoside Monophosphate Prodrugs.

Aryloxy Pivaloyloxymethyl Prodrugs as Nucleoside Monophosphate Prodrugs.

Journal: Journal of medicinal chemistry

Published: November 04, 2021

Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains.

Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains.

Journal: Chembiochem : a European journal of chemical biology

Published: August 22, 2021

Generation of Stable Isopentenyl Monophosphate Aryloxy Triester Phosphoramidates as Activators of Vγ9Vδ2 T Cells.

Generation of Stable Isopentenyl Monophosphate Aryloxy Triester Phosphoramidates as Activators of Vγ9Vδ2 T Cells.

Journal: ChemMedChem

Published: March 22, 2021

A two-pronged attack on antibiotic-resistant microbes.

A two-pronged attack on antibiotic-resistant microbes.

Journal: Nature

Published: January 12, 2021

Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses.

Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses.

Journal: Journal of medicinal chemistry

Published: September 15, 2020

SPAK and OSR1 kinases bind and phosphorylate the β2-Adrenergic receptor.

SPAK and OSR1 kinases bind and phosphorylate the β2-Adrenergic receptor.

Journal: Biochemical and biophysical research communications

Published: July 27, 2020

Aryloxy Triester Phosphoramidates as Phosphoserine Prodrugs: A Proof of Concept Study.

Aryloxy Triester Phosphoramidates as Phosphoserine Prodrugs: A Proof of Concept Study.

Journal: ChemMedChem

Published: January 21, 2020

The Cul4-DDB1-WDR3/WDR6 Complex Binds SPAK and OSR1 Kinases in a Phosphorylation-Dependent Manner.

The Cul4-DDB1-WDR3/WDR6 Complex Binds SPAK and OSR1 Kinases in a Phosphorylation-Dependent Manner.

Journal: Chembiochem : a European journal of chemical biology

Published: July 22, 2019

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Last Updated: 09/26/2026