Young-guen S. Kwon

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 117 publications

A novel Tie2xVEGF bispecific antibody fusion demonstrates enhanced therapeutic efficacy through direct Tie2 activation and VEGF neutralization.

A novel Tie2xVEGF bispecific antibody fusion demonstrates enhanced therapeutic efficacy through direct Tie2 activation and VEGF neutralization.

Journal: Journal of translational medicine
Published: March 03, 2026

CU104, a novel barrier function enhancer, improves colitis via modulation of barrier function and immune cell recruitment.

CU104, a novel barrier function enhancer, improves colitis via modulation of barrier function and immune cell recruitment.

Journal: Frontiers in immunology
Published: December 15, 2025

CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation.

CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation.

Journal: Frontiers in pharmacology
Published: August 13, 2025

The REDD1-NF-κB-miRNAs-eNOS/SIRT1 axis mediates obesity-induced endothelial cell senescence and hypertension.

The REDD1-NF-κB-miRNAs-eNOS/SIRT1 axis mediates obesity-induced endothelial cell senescence and hypertension.

Journal: Nature communications
Published: January 01, 2025

Publisher Correction: Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion.

Publisher Correction: Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion.

Journal: Experimental & molecular medicine
Published: July 18, 2024

Correction to: Nitrosylation of β2-Tubulin Promotes Microtubule Disassembly and Differentiated Cardiomyocyte Beating in Ischemic Mice.

Correction to: Nitrosylation of β2-Tubulin Promotes Microtubule Disassembly and Differentiated Cardiomyocyte Beating in Ischemic Mice.

Journal: Tissue engineering and regenerative medicine
Published: November 08, 2023

CU06-1004 alleviates oxidative stress and inflammation on folic acid-induced acute kidney injury in mice.

CU06-1004 alleviates oxidative stress and inflammation on folic acid-induced acute kidney injury in mice.

Journal: Journal of pharmacological sciences
Published: October 30, 2023

Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion.

Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion.

Journal: Experimental & molecular medicine
Published: October 07, 2023

A novel small molecule, CU05-1189, targeting the pleckstrin homology domain of PDK1 suppresses VEGF-mediated angiogenesis and tumor growth by blocking the Akt signaling pathway.

A novel small molecule, CU05-1189, targeting the pleckstrin homology domain of PDK1 suppresses VEGF-mediated angiogenesis and tumor growth by blocking the Akt signaling pathway.

Journal: Frontiers in pharmacology
Published: August 10, 2023

CU06-1004 as a promising strategy to improve anti-cancer drug efficacy by preventing vascular leaky syndrome.

CU06-1004 as a promising strategy to improve anti-cancer drug efficacy by preventing vascular leaky syndrome.

Journal: Frontiers in pharmacology
Published: June 20, 2023

Nitrosylation of β2-Tubulin Promotes Microtubule Disassembly and Differentiated Cardiomyocyte Beating in Ischemic Mice.

Nitrosylation of β2-Tubulin Promotes Microtubule Disassembly and Differentiated Cardiomyocyte Beating in Ischemic Mice.

Journal: Tissue engineering and regenerative medicine
Published: April 13, 2023

The stress-responsive protein REDD1 and its pathophysiological functions.

The stress-responsive protein REDD1 and its pathophysiological functions.

Journal: Experimental & molecular medicine
Published: March 11, 2023
Showing 1-12 of 117

Last Updated: 09/26/2026